Distribution of Anterior Chamber Angle Width and Correlation With Age, Refraction, and Anterior Chamber Depth-The Gutenberg Health Study.

Schuster, Alexander K; Pfeiffer, Norbert; Nickels, Stefan; Schulz, Andreas; Höhn, René; Wild, Philipp S; Binder, Harald; Münzel, Thomas; Beutel, Manfred E; Vossmerbaeumer, Urs (2016). Distribution of Anterior Chamber Angle Width and Correlation With Age, Refraction, and Anterior Chamber Depth-The Gutenberg Health Study. Investigative ophthalmology & visual science, 57(8), pp. 3740-3746. Association for Research in Vision and Ophthalmology 10.1167/iovs.16-19600

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PURPOSE Scheimpflug imaging allows quantitative analysis of the width of the anterior chamber angle. We report the population-based distribution of the anterior chamber angle width using this noncontact imaging technique and investigate associated factors. METHODS A population-based cross-sectional study was carried out in Germany. A comprehensive ophthalmologic examination including refraction, biometry, and Scheimpflug imaging was performed. Automated measurement of the anterior chamber angle was performed in each anterior chamber quadrant. Exclusion criteria were previous ocular surgery or inadequate image quality. Association analyses were carried out to determine independently associated systemic and ocular factors for anterior chamber angle width using a generalized estimating equation model. RESULTS A total of 3014 subjects (48% female) with a mean age of 58.6 ± 10.4 years were included in this study. The mean anterior chamber angle width was 32.6° ± 5.5°. Statistical analysis revealed an independent association between a smaller anterior chamber angle and female sex, higher age, and more hyperopic refraction. When including biometric parameters, shallow anterior chamber depth, shorter axial length, higher central corneal thickness, and lower corneal power were independently associated with a narrower mean anterior chamber angle width. CONCLUSIONS These parameters are considered risk factors for angle-closure glaucoma.

Item Type:

Journal Article (Original Article)

Division/Institute:

04 Faculty of Medicine > Department of Head Organs and Neurology (DKNS) > Clinic of Ophthalmology

UniBE Contributor:

Höhn, René Gerhard Joachim

Subjects:

600 Technology > 610 Medicine & health

ISSN:

0146-0404

Publisher:

Association for Research in Vision and Ophthalmology

Language:

English

Submitter:

René Gerhard Joachim Höhn

Date Deposited:

02 Mar 2018 10:08

Last Modified:

25 Oct 2019 00:47

Publisher DOI:

10.1167/iovs.16-19600

PubMed ID:

27415792

BORIS DOI:

10.7892/boris.108318

URI:

https://boris.unibe.ch/id/eprint/108318

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