Genomic comparison of bovine papillomavirus 1 isolates from bovine, equine and asinine lesional tissue samples.

Koch, Christoph; Ramsauer, A S; Drögemüller, Michaela; Ackermann, M; Gerber, Vinzenz; Tobler, K (2018). Genomic comparison of bovine papillomavirus 1 isolates from bovine, equine and asinine lesional tissue samples. Virus research, 244, pp. 6-12. Elsevier 10.1016/j.virusres.2017.11.005

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Several attempts have been made to categorize equid- and bovid-specific bovine papillomavirus 1 (BPV1) isolates based on sequence tags. This study includes newly determined sequence information from 33 BPV1 isolates of equine, asinine and bovine origin and investigates sequence bias due to host species. Twenty of the viral genomes were sequenced over their entire length and a further thirteen were sequenced, including flanking sequences, at two specific sites, the LCR and the E5 ORF. Alignment and analyses of the sequences did not reveal statistically significant site differences between the sequences of bovine and equid origin. None of the proposed sites of divergence noted by other authors demonstrated significant species-specific characteristics. Our results suggest that BPV1 is shared between equine, asinine and bovine host species, and that viral transfer between bovines and equids is a repeated and ongoing phenomenon.

Item Type:

Journal Article (Original Article)

Division/Institute:

05 Veterinary Medicine > Research Foci > DermFocus
05 Veterinary Medicine > Research Foci > Host-Pathogen Interaction
05 Veterinary Medicine > Department of Clinical Veterinary Medicine (DKV) > Equine Clinic
05 Veterinary Medicine > Department of Clinical Veterinary Medicine (DKV)
05 Veterinary Medicine > Department of Clinical Research and Veterinary Public Health (DCR-VPH) > Institute of Genetics
05 Veterinary Medicine > Department of Clinical Research and Veterinary Public Health (DCR-VPH)

UniBE Contributor:

Koch, Christoph; Drögemüller, Michaela and Gerber, Vinzenz

Subjects:

600 Technology > 630 Agriculture

ISSN:

0168-1702

Publisher:

Elsevier

Language:

English

Submitter:

Andrea Gassmann-Suter

Date Deposited:

19 Apr 2018 13:49

Last Modified:

08 Feb 2019 09:04

Publisher DOI:

10.1016/j.virusres.2017.11.005

PubMed ID:

29113823

Uncontrolled Keywords:

Bovine papillomavirus Donkey Horse Sarcoid Species-specific variants

BORIS DOI:

10.7892/boris.108375

URI:

https://boris.unibe.ch/id/eprint/108375

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