Myths and misconceptions concerning contrast media-induced anaphylaxis: a narrative review.

Böhm, Ingrid; Morelli, John; Nairz, Knud; Silva Hasembank de Licini, Patricia; Heverhagen, Johannes (2017). Myths and misconceptions concerning contrast media-induced anaphylaxis: a narrative review. Postgraduate medicine, 129(2), pp. 259-266. Taylor & Francis 10.1080/00325481.2017.1282296

Full text not available from this repository. (Request a copy)

Contrast-enhanced radiological examinations are an increasingly important diagnostic tool in modern medicine. All approved and available contrast media (iodinated and gadolinium-based) are safe compounds that are well-tolerated by most patients. However, a small percentage of patients exhibit contrast medium-induced adverse drug reactions that are dose-dependent and predictable (type A) or an even smaller cohort experience so-called type B (dose-independent, non-predictable). To increase patients' safety, recommendations/guidelines have been put forth in the literature and advice passed down informally by radiologists in practice to ensure contrast media safety. Through these, both reasonable suggestions as well as misinterpretations and myths (such as the misleading terms "allergy-like" reactions, and "iodine-allergy", the wrong assumption that the initial contact to a contrast medium could not induce an allergy, the estimation that an anti-allergy premedication could suppress all possible adverse reactions, and interleukin-2 as a risk/trigger for contrast medium adverse events) have arisen. Since the latter are not only unhelpful but also potentially reduce patients' safety, such myths and misconceptions are the focus of this review.

Item Type:

Journal Article (Review Article)

Division/Institute:

04 Faculty of Medicine > Department of Radiology, Neuroradiology and Nuclear Medicine (DRNN) > Institute of Diagnostic, Interventional and Paediatric Radiology
04 Faculty of Medicine > Pre-clinic Human Medicine > BioMedical Research (DBMR) > DBMR Forschung Mu35 > Forschungsgruppe Radiologie
04 Faculty of Medicine > Pre-clinic Human Medicine > BioMedical Research (DBMR) > DBMR Forschung Mu35 > Forschungsgruppe Radiologie

UniBE Contributor:

Böhm, Ingrid; Nairz, Knud; Silva Hasembank de Licini, Patricia and Heverhagen, Johannes

Subjects:

600 Technology > 610 Medicine & health

ISSN:

1941-9260

Publisher:

Taylor & Francis

Language:

English

Submitter:

Nicole Rösch

Date Deposited:

27 Feb 2018 16:04

Last Modified:

27 Feb 2018 16:04

Publisher DOI:

10.1080/00325481.2017.1282296

PubMed ID:

28085538

Uncontrolled Keywords:

Contrast media allergy allergy-like drug hypersensitivity drug safety premedication recombinant interleukin 2 protein

URI:

https://boris.unibe.ch/id/eprint/108404

Actions (login required)

Edit item Edit item
Provide Feedback