The tumour-suppressive miR-29a/b1 cluster is regulated by CEBPA and blocked in human AML

Eyholzer, M; Schmid, S; Wilkens, L; Mueller, B U; Pabst, T (2010). The tumour-suppressive miR-29a/b1 cluster is regulated by CEBPA and blocked in human AML. British journal of cancer, 103(2), pp. 275-84. Basingstoke: Nature Publishing Group 10.1038/sj.bjc.6605751

Full text not available from this repository. (Request a copy)

CCAAT/enhancer-binding protein-alpha (CEBPA) is crucial for normal granulopoiesis and is frequently disrupted in acute myeloid leukaemia (AML). Increasing evidence suggests that CEBPA exerts its effects, in parts, by regulating specific microRNAs (miRNAs), as previously shown for miR-223. The aim of this study was to investigate the genome-wide pattern of miRNAs regulated by CEBPA in myeloid cells.

Item Type:

Journal Article (Original Article)

Division/Institute:

04 Faculty of Medicine > Department of General Internal Medicine (DAIM) > Clinic of General Internal Medicine > Centre of Competence for General Internal Medicine
04 Faculty of Medicine > Department of Haematology, Oncology, Infectious Diseases, Laboratory Medicine and Hospital Pharmacy (DOLS) > Clinic of Medical Oncology

UniBE Contributor:

Müller, Beatrice Ursula and Pabst, Thomas

ISSN:

0007-0920

Publisher:

Nature Publishing Group

Language:

English

Submitter:

Factscience Import

Date Deposited:

04 Oct 2013 14:09

Last Modified:

04 May 2014 23:05

Publisher DOI:

10.1038/sj.bjc.6605751

PubMed ID:

20628397

Web of Science ID:

000279892300017

URI:

https://boris.unibe.ch/id/eprint/1086 (FactScience: 201833)

Actions (login required)

Edit item Edit item
Provide Feedback