Dessauges, Coralie; Pertz, Olivier (2017). Developmental ERK Signaling Goes Digital. Developmental cell, 42(5), pp. 443-444. Cell Press 10.1016/j.devcel.2017.08.023
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Reporting in Developmental Cell, de la Cova et al. (2017) present a biosensor to measure ERK activity dynamics in C. elegans larvae. They find that fate decision signaling involves frequency-modulated, digital ERK activity pulses. These findings may explain how graded morphogen signals are converted into precise and robust cell fate patterns.
Item Type: |
Journal Article (Further Contribution) |
|---|---|
Division/Institute: |
08 Faculty of Science > Department of Biology > Institute of Cell Biology |
UniBE Contributor: |
Dessauges, Coralie, Pertz, Olivier |
Subjects: |
500 Science > 570 Life sciences; biology |
ISSN: |
1534-5807 |
Publisher: |
Cell Press |
Language: |
English |
Submitter: |
Olivier Pertz |
Date Deposited: |
19 Feb 2018 15:41 |
Last Modified: |
05 Dec 2022 15:09 |
Publisher DOI: |
10.1016/j.devcel.2017.08.023 |
PubMed ID: |
28898676 |
Additional Information: |
Expert opinion |
BORIS DOI: |
10.7892/boris.109211 |
URI: |
https://boris.unibe.ch/id/eprint/109211 |
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