Developmental ERK Signaling Goes Digital.

Dessauges, Coralie; Pertz, Olivier (2017). Developmental ERK Signaling Goes Digital. Developmental cell, 42(5), pp. 443-444. Cell Press 10.1016/j.devcel.2017.08.023

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Reporting in Developmental Cell, de la Cova et al. (2017) present a biosensor to measure ERK activity dynamics in C. elegans larvae. They find that fate decision signaling involves frequency-modulated, digital ERK activity pulses. These findings may explain how graded morphogen signals are converted into precise and robust cell fate patterns.

Item Type:

Journal Article (Further Contribution)

Division/Institute:

08 Faculty of Science > Department of Biology > Institute of Cell Biology

UniBE Contributor:

Dessauges, Coralie and Pertz, Olivier

Subjects:

500 Science > 570 Life sciences; biology

ISSN:

1534-5807

Publisher:

Cell Press

Language:

English

Submitter:

Olivier Pertz

Date Deposited:

19 Feb 2018 15:41

Last Modified:

19 Feb 2018 15:44

Publisher DOI:

10.1016/j.devcel.2017.08.023

PubMed ID:

28898676

Additional Information:

Expert opinion

BORIS DOI:

10.7892/boris.109211

URI:

https://boris.unibe.ch/id/eprint/109211

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