Influence of demographic characteristics on attenuated positive psychotic symptoms in a young, help-seeking, at-risk population

Theodoridou, Anastasia; Hengartner, Michael P.; Heekeren, Karsten; Dvorsky, Diane; Schultze-Lutter, Frauke; Gerstenberg, Miriam; Walitza, Susanne; Rössler, Wulf (2019). Influence of demographic characteristics on attenuated positive psychotic symptoms in a young, help-seeking, at-risk population. Early intervention in psychiatry, 13(1), pp. 53-56. Blackwell Publishing Asia 10.1111/eip.12444

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AIM: Presentation of attenuated positive psychotic symptoms (APS) was reported to be modestly influenced by age, sex and education in a psychosis-risk sample. We re-examined the influence of demographic variables on APS in an independent psychosis-risk sample. METHOD: In a clinical high-risk-sample (N = 188; 13-35 years; 60.1% men), bivariate correlations were examined with Spearman correlations. All other associations were computed with generalized linear models. RESULTS: Inter-correlations between positive symptoms were statistically significant for all but the smallest coefficient (range: r = 0.12-0.49). Age was negatively related to APS (range: OR = 0.53-0.78, all P < .01). Male sex was uniquely related to disorganized communication (OR = 1.46) and a high education-level related negatively to suspiciousness/persecutory ideas (OR = 0.64), perceptual abnormalities/hallucinations (OR = 0.57) and disorganized communication (OR = 0.54). The variance explained by age ranged from R 2  = 0.044 for unusual thought content to R 2  = 0.144 for perceptual abnormalities. CONCLUSION: Our results highlighted the role of age and, thereby, neurodevelopment in psychosis-risk assessment.

Item Type:

Journal Article (Original Article)

Division/Institute:

04 Faculty of Medicine > University Psychiatric Services > University Hospital of Child and Adolescent Psychiatry and Psychotherapy
04 Faculty of Medicine > University Psychiatric Services > University Hospital of Child and Adolescent Psychiatry and Psychotherapy > Research Division

UniBE Contributor:

Schultze-Lutter, Frauke

Subjects:

600 Technology > 610 Medicine & health

ISSN:

1751-7885

Publisher:

Blackwell Publishing Asia

Submitter:

Livia Hug

Date Deposited:

21 Feb 2018 08:53

Last Modified:

23 Oct 2019 20:28

Publisher DOI:

10.1111/eip.12444

PubMed ID:

28417595

Uncontrolled Keywords:

age, clinical-high-risk, early recognition, psychosis, sex

BORIS DOI:

10.7892/boris.109309

URI:

https://boris.unibe.ch/id/eprint/109309

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