Killing of bacteria by copper, cadmium, and silver surfaces reveals relevant physicochemical parameters.

Luo, Jiaqi; Hein, Christina; Mücklich, Frank; Solioz, Marc (2017). Killing of bacteria by copper, cadmium, and silver surfaces reveals relevant physicochemical parameters. Biointerphases, 12(2), 020301. American Vacuum Society 10.1116/1.4980127

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The killing of bacteria on metallic copper surfaces in minutes to hours is referred to as contact killing. Why copper possesses such strong antimicrobial activity has remained enigmatic. Based on the physicochemical properties of metals, it was recently predicted that cadmium should also be active in contact killing [Hans et al., Biointerphases 11, 018902 (2010)]. Here, the authors show that cadmium is indeed antimicrobial. It kills three logs of bacteria in 9 h, compared to copper which kills eight logs of bacteria. Metallic silver kills less than one log of bacteria in 9 h. These findings support the novel concept whereby oxide formation, metal ion dissolution, and a Pearson soft character are the key factors for a metal to be antibacterial. Based on these parameters, copper and cadmium are expected to be the two most antibacterial metals.

Item Type:

Journal Article (Original Article)

Division/Institute:

04 Faculty of Medicine > Pre-clinic Human Medicine > BioMedical Research (DBMR) > DBMR Forschung Mu35 > Forschungsgruppe Hepatologie
04 Faculty of Medicine > Pre-clinic Human Medicine > BioMedical Research (DBMR) > DBMR Forschung Mu35 > Forschungsgruppe Hepatologie

04 Faculty of Medicine > Pre-clinic Human Medicine > BioMedical Research (DBMR)

UniBE Contributor:

Solioz, Marc

Subjects:

600 Technology > 610 Medicine & health

ISSN:

1934-8630

Publisher:

American Vacuum Society

Language:

English

Submitter:

Thi Thao Anh Pham

Date Deposited:

06 Feb 2018 10:45

Last Modified:

23 Oct 2019 05:03

Publisher DOI:

10.1116/1.4980127

PubMed ID:

28407716

BORIS DOI:

10.7892/boris.109643

URI:

https://boris.unibe.ch/id/eprint/109643

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