Trojan, Michael; Rengier, Fabian; Kotelis, Drosos; Müller-Eschner, Matthias; Partovi, Sasan; Fink, Christian; Karmonik, Christof; Böckler, Dittmar; Kauczor, Hans-Ulrich; von Tengg-Kobligk, Hendrik (2017). Time-Resolved Three-Dimensional Contrast-Enhanced Magnetic Resonance Angiography in Patients with Chronic Expanding and Stable Aortic Dissections. Contrast media & molecular imaging, 2017, p. 5428914. Wiley 10.1155/2017/5428914
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Time-Resolved Three-Dimensional Contrast-enhanced magnetic resonance.pdf - Published Version Available under License Creative Commons: Attribution (CC-BY). Download (895kB) | Preview |
Objective
To prospectively evaluate our hypothesis that three-dimensional time-resolved contrast-enhanced magnetic resonance angiography (TR-MRA) is able to detect hemodynamic alterations in patients with chronic expanding aortic dissection compared to stable aortic dissections.
Materials and Methods
20 patients with chronic or residual aortic dissection in the descending aorta and patent false lumen underwent TR-MRA of the aorta at 1.5 T and repeated follow-up imaging (mean follow-up 5.4 years). 7 patients showed chronic aortic expansion and 13 patients had stable aortic diameters. Regions of interest were placed in the nondissected ascending aorta and the false lumen of the descending aorta at the level of the diaphragm (FL-diaphragm level) resulting in respective time-intensity curves.
Results
For the FL-diaphragm level, time-to-peak intensity and full width at half maximum were significantly shorter in the expansion group compared to the stable group (p = 0.027 and p = 0.003), and upward and downward slopes of time-intensity curves were significantly steeper (p = 0.015 and p = 0.005). The delay of peak intensity in the FL-diaphragm level compared to the nondissected ascending aorta was significantly shorter in the expansion group compared to the stable group (p = 0.01).
Conclusions
3D TR-MRA detects significant alterations of hemodynamics within the patent false lumen of chronic expanding aortic dissections compared to stable aortic dissections.
Item Type: |
Journal Article (Original Article) |
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Division/Institute: |
04 Faculty of Medicine > Department of Radiology, Neuroradiology and Nuclear Medicine (DRNN) > Institute of Diagnostic, Interventional and Paediatric Radiology 04 Faculty of Medicine > Pre-clinic Human Medicine > BioMedical Research (DBMR) > DBMR Forschung Mu35 > Forschungsgruppe Radiologie 04 Faculty of Medicine > Pre-clinic Human Medicine > BioMedical Research (DBMR) > DBMR Forschung Mu35 > Forschungsgruppe Radiologie |
UniBE Contributor: |
von Tengg-Kobligk, Hendrik |
Subjects: |
600 Technology > 610 Medicine & health |
ISSN: |
1555-4309 |
Publisher: |
Wiley |
Language: |
English |
Submitter: |
Nicole Rösch |
Date Deposited: |
14 Mar 2018 16:31 |
Last Modified: |
05 Dec 2022 15:09 |
Publisher DOI: |
10.1155/2017/5428914 |
PubMed ID: |
29317855 |
BORIS DOI: |
10.7892/boris.109715 |
URI: |
https://boris.unibe.ch/id/eprint/109715 |
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