Cortical thickness, resting state heart rate, and heart rate variability in female adolescents

Koenig, Julian; Parzer, Peter; Reichl, Corinna; Ando, Ayaka; Thayer, Julian F.; Brunner, Romuald; Kaess, Michael (2018). Cortical thickness, resting state heart rate, and heart rate variability in female adolescents. Psychophysiology, 55(5), e13043. Wiley-Blackwell 10.1111/psyp.13043

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Resting state heart rate variability (HRV) is a psychophysiological marker that has gained increasing research interest, in particular in developmental neuroscience. HRV has been shown to be associated with mental and physical health, beyond simple measures of heart rate (HR) and shows inter- and intraindividual variance across aging. Recently, three studies reported on a positive correlation between resting state HRV and cortical thickness in selected regions of interest (ROIs) in adult samples. Structural thickness, HRV, and HR change during the sensitive period of adolescence. Previously, no study has addressed the structural concomitants of resting HR and HRV in adolescents. Cortical thickness (3-T MRI), HR, and HRV were recorded in 20 healthy, female adolescents (mean age: 15.92 years; SD = 1.06; range: 14-17). In line with existing research in adults, cortical thickness in a number of ROIs was associated with resting state HRV but not HR. The comparison of regression analyses using the Bayes factor revealed evidence for a correlation between HRV and cortical thickness of the bilateral rostral anterior cingulate cortex. However, unlike in adults, greater cortical thickness was associated with reduced HRV in female adolescents. Analyses on HR showed no superior model fit. Results suggest that greater HRV might be beneficial for cortical development during adolescence (cortical thinning). On the other hand, cortical development might determine changes in autonomic nervous system function in adolescents. Future studies are needed to replicate these findings in larger samples including boys and to test these hypotheses in longitudinal designs.

Item Type:

Journal Article (Original Article)

Division/Institute:

04 Faculty of Medicine > University Psychiatric Services > University Hospital of Child and Adolescent Psychiatry and Psychotherapy
04 Faculty of Medicine > University Psychiatric Services > University Hospital of Child and Adolescent Psychiatry and Psychotherapy > Research Division

UniBE Contributor:

Koenig, Julian; Reichl, Corinna and Kaess, Michael

Subjects:

600 Technology > 610 Medicine & health

ISSN:

0048-5772

Publisher:

Wiley-Blackwell

Language:

English

Submitter:

Livia Hug

Date Deposited:

14 Mar 2018 17:07

Last Modified:

22 Oct 2019 22:20

Publisher DOI:

10.1111/psyp.13043

PubMed ID:

29215142

Uncontrolled Keywords:

adolescents, cortical thickness, heart rate, heart rate variability, pubertal development, vagal activity

BORIS DOI:

10.7892/boris.109804

URI:

https://boris.unibe.ch/id/eprint/109804

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