Targeting the gut-liver axis in liver disease.

Wiest, Reiner; Albillos, Agustin; Trauner, Michael; Bajaj, Jasmohan S; Jalan, Rajiv (2017). Targeting the gut-liver axis in liver disease. Journal of hepatology, 67(5), pp. 1084-1103. Elsevier 10.1016/j.jhep.2017.05.007

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The gut-liver axis is widely implicated in the pathogenesis of liver diseases, where it is increasingly the focus of clinical research. Recent studies trialling an array of therapeutic and preventative strategies have yielded promising results. Considering these strategies, the armamentarium for targeting the gut-liver axis will continue to expand. Further clinical trials, translated from our current knowledge of the gut-liver axis, promise an exciting future in liver treatment.

Item Type:

 Journal Article (Review Article)

Division/Institute:

 04 Faculty of Medicine > Department of Gastro-intestinal, Liver and Lung Disorders (DMLL) > Clinic of Visceral Surgery and Medicine > Gastroenterology
04 Faculty of Medicine > Pre-clinic Human Medicine > BioMedical Research (DBMR) > DBMR Forschung Mu35 > Forschungsgruppe Gastroenterologie / Mukosale Immunologie
04 Faculty of Medicine > Pre-clinic Human Medicine > BioMedical Research (DBMR) > DBMR Forschung Mu35 > Forschungsgruppe Gastroenterologie / Mukosale Immunologie

UniBE Contributor:

 Wiest, Reiner

Subjects:

 600 Technology > 610 Medicine & health

ISSN:

 0168-8278

Publisher:

 Elsevier

Language:

 English

Submitter:

 Thi Thao Anh Pham

Date Deposited:

 30 Jan 2018 15:10

Last Modified:

 05 Dec 2022 15:10

Publisher DOI:

 10.1016/j.jhep.2017.05.007

Related URLs:

PubMed ID:

 28526488

Uncontrolled Keywords:

 Bacterial translocation Bile acids Cirrhosis Faecal microbial transplantation Fibrosis Gut-liver-axis Incretines Liver injury Microbiome Pre-, probiotics

BORIS DOI:

 10.7892/boris.110319

URI:

 https://boris.unibe.ch/id/eprint/110319

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