Sequence analysis of leg movements during sleep with different intervals (<10, 10-90 and >90 s) in restless legs syndrome.

Ferri, Raffaele; Rundo, Francesco; Silvani, Alessandro; Zucconi, Marco; Aricò, Debora; Bruni, Oliviero; Cosentino, Filomena I I; Ferini-Strambi, Luigi; Manconi, Mauro (2017). Sequence analysis of leg movements during sleep with different intervals (<10, 10-90 and >90 s) in restless legs syndrome. Journal of sleep research, 26(4), pp. 436-443. Wiley-Blackwell 10.1111/jsr.12500

[img] Text
jsr12500.pdf - Published Version
Restricted to registered users only
Available under License Publisher holds Copyright.

Download (427kB) | Request a copy

The aim of this study was to define the time structure of leg movements during sleep occurring with an intermovement interval (onset-to-onset) shorter than 10 s in patients with restless legs syndrome and controls, and to compare it to the structure of movements with intervals of 10-90 s or >90 s. Polysomnographic recordings of 141 untreated patients and 68 age-matched normal controls were analysed. All movements were detected and classified into three categories, separated by intervals of <10, 10-90 or >90 s. The number of movements included in each category was significantly higher in patients than in controls. The movements with an interval of >90 s occurred steadily during the night, whereas the hourly distribution of movements with intervals of <10 or 10-90 s was decreasing or bell-shaped in patients or controls, respectively. Movements with an interval of <10 s tended to have a shorter duration and constituted shorter sequences than movements with intervals of 10-90 or >90 s. The time structure features of the three categories of movements considered in this study were found to be clearly different. This, together with previous observations on the differential effects of dopamine agonists on movements with different intervals, suggests that movements with intervals of <10 and >90 s are regulated by neurotransmitter mechanisms different from those modulating movements with an interval of 10-90 s.

Item Type:

Journal Article (Original Article)

Division/Institute:

04 Faculty of Medicine > Department of Head Organs and Neurology (DKNS) > Clinic of Neurology

UniBE Contributor:

Manconi, Mauro

Subjects:

600 Technology > 610 Medicine & health

ISSN:

0962-1105

Publisher:

Wiley-Blackwell

Language:

English

Submitter:

Stefanie Hetzenecker

Date Deposited:

08 Mar 2018 11:12

Last Modified:

16 Jul 2018 15:25

Publisher DOI:

10.1111/jsr.12500

PubMed ID:

28127802

Uncontrolled Keywords:

Willis-Ekbom Disease periodic leg movements during sleep short intermovement interval leg movements during sleep time structure

BORIS DOI:

10.7892/boris.111014

URI:

https://boris.unibe.ch/id/eprint/111014

Actions (login required)

Edit item Edit item
Provide Feedback