Resistance to carbapenems: mechanisms and detection methods

Endimiani, Andrea (20 September 2017). Resistance to carbapenems: mechanisms and detection methods (Unpublished). In: XXII Congreso Latinoamericano de Bioquímica Clínica. Punta del Este, Uruguay. 20.09.2017.

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In the last two decades, carbapenems have been implemented for the treatment of infections due to last-generation cephalosporin-resistant Gram-negative infections. This massive use has contributed to the selection of carbapenem-resistant bugs that usually produce carbapenemase enzymes. Nowadays, the spread of such untreatable organisms has reached dramatic levels representing one of the most global public health problems. This issue has led to the realization of the need for more rapid diagnosis. This talk presents a summary of the carbapenem resistance mechanisms. In particular, the main classes of carbapenemases will be discussed, emphasizing on their genetic background that support global spread. The currently available phenotypic and molecular methods that can be implemented by diagnostic and research laboratories will be also debated.

Item Type:

Conference or Workshop Item (Speech)

Division/Institute:

04 Faculty of Medicine > Service Sector > Institute for Infectious Diseases

UniBE Contributor:

Endimiani, Andrea

Subjects:

500 Science
500 Science > 570 Life sciences; biology

Projects:

[577] SNF project 153377 to Andrea Endimiani

Language:

Español

Submitter:

Andrea Endimiani

Date Deposited:

22 Feb 2018 15:32

Last Modified:

25 Oct 2019 20:41

BORIS DOI:

10.7892/boris.111031

URI:

https://boris.unibe.ch/id/eprint/111031

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