Interventions to reduce the risk of ovarian and fallopian tube cancer: A European Menopause and Andropause Society Postition Statement.

Pérez-López, Faustino R; Ceausu, Iuliana; Depypere, Herman; Kehoe, Sean; Lambrinoudaki, Irene; Mueck, Alfred; Senturk, Levent M; Simoncini, Tommaso; Stevenson, John C; Stute, Petra; Rees, Margaret (2017). Interventions to reduce the risk of ovarian and fallopian tube cancer: A European Menopause and Andropause Society Postition Statement. Maturitas, 100, pp. 86-91. Elsevier 10.1016/j.maturitas.2017.03.003

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BACKGROUND Ovarian cancer is a leading cause of female gynecological cancer-related death, and there are no effective screening procedures or early diagnostic approaches. AIMS To examine risk factors and risk-reducing strategies for both sporadic and familial tumors. MATERIALS AND METHODS Literature review and consensus of expert opinion. RESULTS AND CONCLUSIONS In women with a genetic predisposition to ovarian cancer, salpingo-oophorectomy reduces the risk of ovarian malignancy, and to a lesser degree of breast cancer. Opportunistic bilateral salpingo-oophorectomy and bilateral salpingectomy may also prevent epithelial ovarian cancer. In premenopausal women, bilateral salpingectomy should be preferred to tubal ligation, and be performed when hysterectomy is carried out for benign uterine disease. Hysterectomy and the use of combined oral contraceptives and non-steroid anti-inflammatory drugs are also recognized to reduce the risk of ovarian cancer, as do the prevention of obesity and smoking cessation.

Item Type:

Journal Article (Review Article)

Division/Institute:

04 Faculty of Medicine > Department of Gynaecology, Paediatrics and Endocrinology (DFKE) > Clinic of Gynaecology

UniBE Contributor:

Stute, Petra

Subjects:

600 Technology > 610 Medicine & health

ISSN:

0378-5122

Publisher:

Elsevier

Language:

English

Submitter:

Monika Zehr

Date Deposited:

08 Mar 2018 15:27

Last Modified:

08 Mar 2018 15:27

Publisher DOI:

10.1016/j.maturitas.2017.03.003

PubMed ID:

28389043

Uncontrolled Keywords:

BRCA gene mutation Bilateral oophorectomy Bilateral salpingectomy Combined oral contraceptives Fallopian tubes cancer Hysterectomy Non-steroid anti-inflammatory drugs Obesity Ovarian borderline tumors Ovarian cancer Smoking

BORIS DOI:

10.7892/boris.111138

URI:

https://boris.unibe.ch/id/eprint/111138

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