[Nerve distribution and density in the canine hip joint capsule. Comparison of healthy and dysplastic hip joints].

Giebels, Felix; Prescher, A; Wagenpfeil, S; Bücker, A; Kinzel, S (2017). [Nerve distribution and density in the canine hip joint capsule. Comparison of healthy and dysplastic hip joints]. Tierärztliche Praxis. Ausgabe K - Kleintiere, Heimtiere, 45(2), pp. 77-83. Schattauer 10.15654/TPK-160366

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OBJECTIVE:

The hip-joint capsule is exposed to increased tension forces during canine hip dysplasia, resulting in inflammation of the capsular tissue. It has been postulated that inflammation is associated with an increased nerve-distribution density. Therefore, it could be supposed that the nerve-distribution density in the hip-joint capsule is higher in dogs with dysplastic hip compared to healthy dogs.
MATERIAL AND METHODS:

In 16 Labrador Retriever dogs that had been euthanised due to unrelated reasons, the hip joints were classified as normoplastic (group 1, n = 18) or dysplastic (group 2, n = 14) based on radiography. Following staining of the capsular nerve fibres by the Sihler method, histological specimens of the hip-joint capsules were scanned. By subdividing each specimen into 10 quadrants numbered from dorsomedial (Q01) to craniodorsolateral (Q10), the ratio of black to white pixels was calculated digitally for each specimen and each quadrant by using a semiautomatic image analysis. Statistical analysis was performed using an independent t-test.
RESULTS:

Comparison of the mean values of each quadrant showed a significantly higher (p < 0.03) nerve distribution density for the craniodorsolateral quadrant (Q10) in group 2 when compared to group 1. Mean nerve-distribution density for all quadrants combined was not significantly different between the two groups.
CONCLUSION:

The increase in nerve-distribution density of the craniodorsal region of the hip-joint capsule in dogs with dysplastic hip could be the result of increased tension forces on this area following hip-joint dysplasia. The craniodorsal region of the hip-joint capsule is an important origin of pain and coxarthrosis in canine hip dysplasia.
CLINICAL RELEVANCE:

The results provide the pathophysiological basis for the efficacy of hip-joint denervation. Denervation of the cranial region of the acetabular rim is essential to reduce capsular inflammation and joint-related pain in canine hip dysplasia.

Item Type:	Journal Article (Original Article)
Division/Institute:	05 Veterinary Medicine > Department of Clinical Veterinary Medicine (DKV) > DKV - Clinical Neurology 05 Veterinary Medicine > Department of Clinical Veterinary Medicine (DKV)
UniBE Contributor:	Giebels, Felix
Subjects:	600 Technology > 610 Medicine & health 600 Technology > 630 Agriculture
ISSN:	1434-1239
Publisher:	Schattauer
Language:	German
Submitter:	Veronika Maria Stein
Date Deposited:	08 May 2018 11:15
Last Modified:	05 Dec 2022 15:10
Publisher DOI:	10.15654/TPK-160366
PubMed ID:	28197624
URI:	https://boris.unibe.ch/id/eprint/111450