Canal, Cláudio W; Weber, Matheus N; Cibulski, Samuel P; Silva, Mariana S; Puhl, Daniela E; Stalder, Hanspeter; Peterhans, Ernst (2017). A Novel Genetic Group of Bovine Hepacivirus in Archival Serum Samples from Brazilian Cattle. BioMed research international, 2017(4732520), p. 4732520. Hindawi Publishing Corporation 10.1155/2017/4732520
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Hepatitis C virus (HCV) (genus; family Flaviviridae) is a major human pathogen causing persistent infection and hepatic injury. Recently, emerging HCV-like viruses were described infecting wild animals, such as bats and rodents, and domestic animals, including dogs, horses, and cattle. Using degenerate primers for detecting bovine pestiviruses in a 1996 survey three bovine serum samples showed a low identity with the genusof the Flaviviridae family. A virus could not be isolated in cell culture. The description of bovine hepaciviruses (BovHepV) in 2015 allowed us to retrospectively identify the sequences as BovHepV, with a 88.9% nucleotide identity. In a reconstructed phylogenetic tree, the Brazilian BovHepV samples grouped within the bovine HCV-like cluster in a separated terminal node that was more closely related to the putative bovinecommon ancestor than to bovine hepaciviruses detected in Europe and Africa.
Item Type: |
Journal Article (Original Article) |
|---|---|
Division/Institute: |
05 Veterinary Medicine > Research Foci > Host-Pathogen Interaction 05 Veterinary Medicine > Department of Infectious Diseases and Pathobiology (DIP) > Institute of Virology and Immunology 05 Veterinary Medicine > Department of Infectious Diseases and Pathobiology (DIP) |
UniBE Contributor: |
Stalder, Hanspeter, Peterhans, Ernst |
Subjects: |
600 Technology > 630 Agriculture 500 Science > 570 Life sciences; biology |
ISSN: |
2314-6133 |
Publisher: |
Hindawi Publishing Corporation |
Language: |
English |
Submitter: |
Pamela Schumacher |
Date Deposited: |
08 May 2018 17:00 |
Last Modified: |
05 Dec 2022 15:11 |
Publisher DOI: |
10.1155/2017/4732520 |
PubMed ID: |
28904959 |
BORIS DOI: |
10.7892/boris.112043 |
URI: |
https://boris.unibe.ch/id/eprint/112043 |
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