Osteoblast proliferation and differentiation on a barrier membrane in combination with BMP2 and TGFβ1

Miron, Richard J.; Saulacic, Nikola; Buser, Daniel; Iizuka, Tateyuki; Sculean, Anton (2013). Osteoblast proliferation and differentiation on a barrier membrane in combination with BMP2 and TGFβ1. Clinical oral investigations, 17(3), pp. 981-988. Berlin: Springer-Verlag 10.1007/s00784-012-0764-7

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Bioresorbable collagen membranes are routinely utilized in guided bone regeneration to selectively direct the growth and repopulation of bone cells in areas of insufficient volume. However, the exact nature by which alveolar osteoblasts react to barrier membranes as well as the effects following the addition of growth factors to the membranes are still poorly understood. The objective of the present study was therefore to investigate the effect of a bioresorbable collagen membrane soak-loaded in growth factors bone morphogenetic protein 2 (BMP2) or transforming growth factor β1 (TGFβ1) on osteoblast adhesion, proliferation, and differentiation.

Item Type:

Journal Article (Original Article)

Division/Institute:

04 Faculty of Medicine > School of Dental Medicine > Department of Periodontology
04 Faculty of Medicine > School of Dental Medicine > Department of Oral Surgery and Stomatology
04 Faculty of Medicine > Department of Head Organs and Neurology (DKNS) > Clinic of Craniomaxillofacial Surgery

UniBE Contributor:

Miron, Richard; Saulacic, Nikola; Buser, Daniel; Iizuka, Tateyuki and Sculean, Anton

Subjects:

600 Technology > 610 Medicine & health

ISSN:

1432-6981

Publisher:

Springer-Verlag

Language:

English

Submitter:

Eveline Carmen Schuler

Date Deposited:

04 Oct 2013 14:30

Last Modified:

26 Jun 2018 15:14

Publisher DOI:

10.1007/s00784-012-0764-7

PubMed ID:

22669486

Web of Science ID:

000316749300035

BORIS DOI:

10.7892/boris.11260

URI:

https://boris.unibe.ch/id/eprint/11260 (FactScience: 217333)

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