Aircraft noise, air pollution, and mortality from myocardial infarction

Huss, Anke; Spoerri, Adrian; Egger, Matthias; Röösli, Martin (2010). Aircraft noise, air pollution, and mortality from myocardial infarction. Epidemiology, 21(6), pp. 829-836. Baltimore, Md.: Wolters Kluwer Health, Lippincott Williams & Wilkins 10.1097/EDE.0b013e3181f4e634

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Objective: Myocardial infarction has been associated with both transportation noise and air pollution. We examined residential exposure to aircraft noise and mortality from myocardial infarction, taking air pollution into account. Methods: We analyzed the Swiss National Cohort, which includes geocoded information on residence. Exposure to aircraft noise and air pollution was determined based on geospatial noise and air-pollution (PM10) models and distance to major roads. We used Cox proportional hazard models, with age as the timescale. We compared the risk of death across categories of A-weighted sound pressure levels (dB(A)) and by duration of living in exposed corridors, adjusting for PM10 levels, distance to major roads, sex, education, and socioeconomic position of the municipality. Results: We analyzed 4.6 million persons older than 30 years who were followed from near the end of 2000 through December 2005, including 15,532 deaths from myocardial infarction (ICD-10 codes I 21, I 22). Mortality increased with increasing level and duration of aircraft noise. The adjusted hazard ratio comparing ≥60 dB(A) with <45 dB(A) was 1.3 (95% confidence interval = 0.96-1.7) overall, and 1.5 (1.0-2.2) in persons who had lived at the same place for at least 15 years. None of the other endpoints (mortality from all causes, all circulatory disease, cerebrovascular disease, stroke, and lung cancer) was associated with aircraft noise. Conclusion: Aircraft noise was associated with mortality from myocardial infarction, with a dose-response relationship for level and duration of exposure. The association does not appear to be explained by exposure to particulate matter air pollution, education, or socioeconomic status of the municipality.

Item Type:

Journal Article (Original Article)


04 Faculty of Medicine > Pre-clinic Human Medicine > Institute of Social and Preventive Medicine (ISPM)

UniBE Contributor:

Huss, Anke; Spörri, Adrian and Egger, Matthias




Wolters Kluwer Health, Lippincott Williams & Wilkins




Factscience Import

Date Deposited:

04 Oct 2013 14:09

Last Modified:

11 Sep 2017 20:45

Publisher DOI:


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Web of Science ID:




URI: (FactScience: 201945)

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