Radiosurgery and radiotherapy for arteriovenous malformations: outcome predictors and review of the literature.

Vlaskou Badra, Eugenia; Ermis, Ekin; Mordasini, Pasquale; Herrmann, Evelyn (2018). Radiosurgery and radiotherapy for arteriovenous malformations: outcome predictors and review of the literature. Journal of Neurosurgical Sciences, 62(4), pp. 490-504. Edizione Minerva Medica 10.23736/S0390-5616.18.04406-5

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Arteriovenous malformations (AVMs) are rare congenital vascular pathologies. The reported overall annual hemorrhage rate is 3.0%, for unruptured AVMs it is 2.2%, and for ruptured AVMs, 4.5%. The main goal of AVM treatment is to prevent intracerebral hemorrhage. This is achieved by complete nidus eradication. Interventional treatment options include microsurgery, embolization and radiosurgery, as well as multimodal approaches. Radiosurgery is a safe and effective alternative to surgery or embolization, especially for AVMs located in deep or eloquent brain regions, where invasive treatment cannot be performed. With the introduction of the Leksell Gamma Knife, AVMs became one of the most common indications for radiosurgical interventions (nearly 30% of the first 15-year experience). The current review discusses the role of radiosurgery in the treatment of AVMs, with a focus on outcome predictors and a discussion of the relevant literature.

Item Type:

Journal Article (Review Article)

Division/Institute:

04 Faculty of Medicine > Department of Haematology, Oncology, Infectious Diseases, Laboratory Medicine and Hospital Pharmacy (DOLS) > Clinic of Radiation Oncology
04 Faculty of Medicine > Department of Radiology, Neuroradiology and Nuclear Medicine (DRNN) > Institute of Diagnostic and Interventional Neuroradiology

UniBE Contributor:

Vlaskou Badra, Eugenia; Ermis, Ekin; Mordasini, Pasquale and Herrmann, Evelyn

Subjects:

600 Technology > 610 Medicine & health

ISSN:

0390-5616

Publisher:

Edizione Minerva Medica

Language:

English

Submitter:

Martin Zbinden

Date Deposited:

23 Apr 2018 11:46

Last Modified:

27 Jun 2018 01:31

Publisher DOI:

10.23736/S0390-5616.18.04406-5

PubMed ID:

29582976

URI:

https://boris.unibe.ch/id/eprint/113956

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