Reportings of declarations and conflicts of interest in WHO guidelines can be further improved

Wang, Xiaoqin; Chen, Yaolong; Yao, Liang; Zhou, Qi; Wu, Qiongfang; Estill, Janne Anton Markus; Wang, Qi; Yang, Kehu; Norris, Susan L (2018). Reportings of declarations and conflicts of interest in WHO guidelines can be further improved. Journal of clinical epidemiology, 98, pp. 1-8. Elsevier 10.1016/j.jclinepi.2017.12.021

[img] Text
Wang_et_al_Published.pdf - Published Version
Restricted to registered users only
Available under License Publisher holds Copyright.

Download (416kB) | Request a copy
Manuscript-WHO COI-jce-clear-postprint.pdf - Accepted Version
Available under License Creative Commons: Attribution-Noncommercial-No Derivative Works (CC-BY-NC-ND).

Download (182kB) | Preview

OBJECTIVES We aimed to examine the declaration of interests (DOI), management of conflict of interest (COI), and the funders for World Health Organization (WHO) guidelines. STUDY DESIGN AND SETTING We examined all Guidelines Review Committee (GRC)-approved WHO guidelines published in English from January 2007 (inception of the GRC) to November 2016. We obtained a list of all such guidelines from the GRC Secretariat. Characteristics of guidelines including funders and individual contributors' DOI were independently extracted by two researchers. Binary logistic regression was used to assess the association between declarations and the number of organizations involved in development. RESULTS 176 guidelines fulfilled inclusion criteria, encompassing 14 clinical or public health fields. Funders were reported in 128 (73%) of the guidelines: the most common were governments. DOI for external contributors were reported in 156 (89%) of the guidelines: 75 (48%) indicated no contributors with COI, 56 (36%) reported contributors with COI, and 25 (16%) reported collecting DOI but not whether COI existed. Financial COI were reported more frequently than nonfinancial COI. Of 56 guidelines that reported COI, 44 (79%) indicated how the COI were managed. CONCLUSION The majority of WHO guidelines reported their funding sources, and the DOI and COI of external contributors in their guideline documents. However, there is a need for improvement, in particular for reporting of funders and their role, declaration processes, and management of COI.

Item Type:

Journal Article (Review Article)


08 Faculty of Science > Department of Mathematics and Statistics > Institute of Mathematical Statistics and Actuarial Science

UniBE Contributor:

Estill, Janne Anton Markus


300 Social sciences, sociology & anthropology > 360 Social problems & social services
500 Science > 510 Mathematics








Janne Anton Markus Estill

Date Deposited:

24 Apr 2018 08:25

Last Modified:

24 Oct 2019 11:39

Publisher DOI:


PubMed ID:


Uncontrolled Keywords:

WHO conflicts of interest (COI) declaration of interest (DOI) practice guideline reporting quality




Actions (login required)

Edit item Edit item
Provide Feedback