Demenz und Altersdepression

Leyhe, Thomas; Melcher, Tobias; Linnemann, Christoph; Klöppel, Stefan; Hampel, Harald (2018). Demenz und Altersdepression. Swiss archives of neurology, psychiatry and psychotherapy, 169(3), pp. 70-74. EMH Media 10.4414/sanp.2018.00571

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In old age, depression is often associated with cognitive impairment, dementia is associated with depressive symptoms, depressive symptoms can precede a dementia syndrome, and depression and dementia can occur together.
In addition, depressive disorders increase the risk for the later development of dementia. The current evidence for the benefit of clinical findings, and neuropsychological, neurochemical and imaging biomarkers for the differentiation of dementia and depression, as well as for the prognosis of depression with regard to the risk of dementia is presented.
In addition, current pharmacotherapy and psychotherapy of depression in demented patients is summarised. There is an urgent need for research to elucidate clinical and biological features in older people with depressive disorders who are at an increased risk of developing
dementia.

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