Multi-year inter-laboratory exercises for the analysis of illicit drugs and metabolites in wastewater: Development of a quality control system

van Nuijs, A.L.N.; Lai, F.Y.; Been, F.; Andres-Costa, M.J.; Barron, L.; Baz-Lomba, J.A.; Berset, Jean-Daniel; Benaglia, L.; Bijlsma, L.; Burgard, D.; Castiglioni, S.; Christophoridis, C.; Covaci, A.; de Voogt, P.; Emke, E.; Fatta-Kassinos, D.; Fick, J.; Hernandez, F.; Gerber, C.; González-Mariño, I.; ... (2018). Multi-year inter-laboratory exercises for the analysis of illicit drugs and metabolites in wastewater: Development of a quality control system. Trends in analytical chemistry, 103, pp. 34-43. Elsevier 10.1016/j.trac.2018.03.009

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Thirty-seven laboratories from 25 countries present the development of an inter-laboratory testing scheme for the analysis of seven illicit drug residues in standard solutions, tap- and wastewater. Almost 10 000 concentration values were evaluated: triplicates of up to five samples and 26 laboratories per year. The setup was substantially improved with experiences gained across the six repetitions (e.g. matrix type, sample conditions, spiking levels). From this, (pre-)analytical issues (e.g. pH adjustment, filtration) were revealed for specific analytes which resulted in formulation of best-practice protocols for inter-laboratory setup and analytical procedures. The results illustrate the effectiveness of the inter-laboratory setup to assess laboratory performance in the framework of wastewater-based epidemiology. The exercise proved that measurements of laboratories were of high quality (>80 satisfactory results for six out of seven analytes) and that analytical follow-up is important to assist laboratories in improving robustness of wastewater-based epidemiology results.

Item Type:

Journal Article (Original Article)

Division/Institute:

08 Faculty of Science > Department of Biology > Institute of Plant Sciences (IPS) > Library Plant Sciences
08 Faculty of Science > Department of Biology > Institute of Plant Sciences (IPS)

UniBE Contributor:

Berset, Jean Daniel

Subjects:

500 Science > 580 Plants (Botany)

ISSN:

0165-9936

Publisher:

Elsevier

Language:

English

Submitter:

Peter Alfred von Ballmoos-Haas

Date Deposited:

08 May 2018 15:00

Last Modified:

08 May 2018 15:00

Publisher DOI:

10.1016/j.trac.2018.03.009

Uncontrolled Keywords:

Epidemiology; Filtration; Laboratories; Quality assurance; Wastewater, Analytical procedure; Concentration values; Illicit drug; Inter-laboratory testing; Laboratory exercise; Laboratory performance; Laboratory set-up; Standard solutions, Quality control

BORIS DOI:

10.7892/boris.114857

URI:

https://boris.unibe.ch/id/eprint/114857

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