Excretion of Cannabinoids in Urine after Ingestion of Cannabis Seed Oil

Lehmann, T.; Sager, F.; Brenneisen, R. (1997). Excretion of Cannabinoids in Urine after Ingestion of Cannabis Seed Oil. Journal of analytical toxicology, 21(5), pp. 373-375. Oxford University Press 10.1093/jat/21.5.373

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Gas chromatographic-mass spectrometric (GC-MS) quantitation of 25 cannabis sed oils determined Δ9-tetrahydrocannabinol (THC) concentrations from 3 to 1500 µg/g oil. In a pilot study, the morning urine of six volunteers who had ingested 11 or 22 g of the oil, which contained the highest THC content (1500 µg/g), was collected for six days. The urine samples were screened by immunoassay, and the content of 11-nor-9-carboxy-Δ9-THC (THCCOOH) was determined by GC-MS. Urine samples were found cannabis positive for up to six days with THCCOOH-equivalent concentrations up to 243 ng/ml, by the Abuscreen OnLine immunoassay and THCCOOH contents from 5 to 431 ng/mL by the GC-MS method. All subjects reported THC-specific psychotropic effects.

Item Type:

Journal Article (Original Article)

Division/Institute:

04 Faculty of Medicine > Pre-clinic Human Medicine > BioMedical Research (DBMR) > DBMR Forschung Mu35 > Forschungsgruppe Phytopharmakologie, Bioanalytik & Pharmakokinetik [discontinued]
04 Faculty of Medicine > Pre-clinic Human Medicine > BioMedical Research (DBMR) > DBMR Forschung Mu35 > Forschungsgruppe Phytopharmakologie, Bioanalytik & Pharmakokinetik [discontinued]

UniBE Contributor:

Brenneisen, Rudolf Max

ISSN:

0146-4760

Publisher:

Oxford University Press

Language:

English

Submitter:

Marceline Brodmann

Date Deposited:

02 Sep 2020 16:16

Last Modified:

02 Sep 2020 16:55

Publisher DOI:

10.1093/jat/21.5.373

BORIS DOI:

10.7892/boris.114986

URI:

https://boris.unibe.ch/id/eprint/114986

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