Prevalence and Clinical Significance of Splenomegaly in Asymptomatic Human Immunodeficiency Virus Type 1-Infected Adults

Furrer, Hansjakob (2000). Prevalence and Clinical Significance of Splenomegaly in Asymptomatic Human Immunodeficiency Virus Type 1-Infected Adults. Clinical infectious diseases, 30(6), pp. 943-945. The University of Chicago Press 10.1086/313816

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In a prospective cohort study of 70 consecutive, asymptomatic human immunodeficiency virus type 1 (HIV-1)-infected adults, splenomegaly was found by physical examination in 23% of patients and by ultrasound in 66%. Patients with concomitant liver disease had a higher prevalence of splenomegaly (RR 1.84; P<.001). During a 1-year follow-up of 66 patients, splenomegaly at enrollment was not predictive of any clinical event, and splenomegaly was not associated with a higher risk of developing AIDS during a median follow-up of 6.1 years.

Item Type:

Journal Article (Original Article)

Division/Institute:

04 Faculty of Medicine > Department of Haematology, Oncology, Infectious Diseases, Laboratory Medicine and Hospital Pharmacy (DOLS) > Clinic of Infectiology

UniBE Contributor:

Furrer, Hansjakob

Subjects:

600 Technology > 610 Medicine & health

ISSN:

1058-4838

Publisher:

The University of Chicago Press

Language:

English

Submitter:

Marceline Brodmann

Date Deposited:

29 Oct 2020 15:19

Last Modified:

29 Oct 2020 15:19

Publisher DOI:

10.1086/313816

BORIS DOI:

10.7892/boris.115235

URI:

https://boris.unibe.ch/id/eprint/115235

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