Familial Transmission of a Serious Disease—Producing Group A Streptococcus Clone: Case Reports and Review

Gamba, M.-A.; Martinelli, M.; Schaad, H. J.; Streuli, R. A.; Dipersio, J.; Matter, L.; Ris, H.-B.; Marchal, F.; Kaplan, E. L.; Stevens, D. L.; Malinverni, R. (1997). Familial Transmission of a Serious Disease—Producing Group A Streptococcus Clone: Case Reports and Review. Clinical infectious diseases, 24(6), pp. 1118-1121. The University of Chicago Press 10.1086/513636

[img]
Preview
Text
24-6-1118.pdf - Published Version
Available under License Publisher holds Copyright.

Download (211kB) | Preview

Invasive group A streptococcus (GAS) infections are emerging diseases; however, person-to-person transmission of invasive GAS producing life-threatening infection has been observed rarely. We report a small intrafamilial cluster of life-threatening GAS infections. A previously healthy 47-year-old father developed necrotizing fasciitis of the neck. Two days later, his 16-year-old daughter developed streptococcal angina, pneumonia, and pleural empyema. Both patients had signs of streptococcal toxic shock syndrome. Pulsed field gel electrophoresis revealed that the M6 strains of GAS isolated from the father and daughter had identical patterns. Cases of person-to-person transmission of invasive GAS infection reported in the literature are also reviewed.

Item Type:

Journal Article (Further Contribution)

Division/Institute:

04 Faculty of Medicine > Department of Cardiovascular Disorders (DHGE) > Clinic of Cardiovascular Surgery
04 Faculty of Medicine > Department of Cardiovascular Disorders (DHGE) > Clinic of Cardiology
04 Faculty of Medicine > Department of General Internal Medicine (DAIM) > Clinic of General Internal Medicine > Centre of Competence for General Internal Medicine
04 Faculty of Medicine > Department of Head Organs and Neurology (DKNS) > Clinic of Craniomaxillofacial Surgery

UniBE Contributor:

Martinelli, Michele and Malinverni, Raffaele

Subjects:

600 Technology > 610 Medicine & health

ISSN:

1058-4838

Publisher:

The University of Chicago Press

Language:

English

Submitter:

Marceline Brodmann

Date Deposited:

10 Nov 2020 14:51

Last Modified:

10 Nov 2020 14:51

Publisher DOI:

10.1086/513636

BORIS DOI:

10.7892/boris.115237

URI:

https://boris.unibe.ch/id/eprint/115237

Actions (login required)

Edit item Edit item
Provide Feedback