Müller, N.; Imboden, M.; Detmer, E.; Mansfield, J. M.; Seebeck, T. (1993). Cytoskeleton-associated antigens from African trypanosomes are recognized by self-reactive antibodies of uninfected mice. Parasitology, 107(4), pp. 411-417. Cambridge University Press 10.1017/S0031182000067767
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Serum from uninfected mice of different strains, as well as from germ-free animals, contains antibodies which react specifically with at least two trypanosomal proteins, I/6 and MARP1. These antibody populations are highly specific for the respective proteins, are of similar affinity as hyperimmune antibodies, and consist of IgM as well as IgG isotypes. Hyperimmune antibody raised against the cross-reacting trypanosomal protein I/6 detects a 60 kDa protein in mouse 3T6 cells, which is a component of the fibroblast cytoskeleton.
Item Type: |
Journal Article (Original Article) |
|---|---|
Division/Institute: |
05 Veterinary Medicine > Department of Infectious Diseases and Pathobiology (DIP) > Institute of Parasitology 08 Faculty of Science > Department of Biology > Institute of Cell Biology |
UniBE Contributor: |
Seebeck, Thomas |
Subjects: |
500 Science > 570 Life sciences; biology |
ISSN: |
0031-1820 |
Publisher: |
Cambridge University Press |
Language: |
English |
Submitter: |
Marceline Brodmann |
Date Deposited: |
16 Jul 2020 09:43 |
Last Modified: |
05 Dec 2022 15:13 |
Publisher DOI: |
10.1017/S0031182000067767 |
PubMed ID: |
7506406 |
BORIS DOI: |
10.7892/boris.115441 |
URI: |
https://boris.unibe.ch/id/eprint/115441 |
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