Classification of Mild Cognitive Impairment and Alzheimer Disease Using Model-Based MR and Magnetization Transfer Imaging

Wiest, R; Burren, Y; Hauf, M; Schroth, G; Pruessner, J; Zbinden, M; Cattapan-Ludewig, K; Kiefer, C (2013). Classification of Mild Cognitive Impairment and Alzheimer Disease Using Model-Based MR and Magnetization Transfer Imaging. American journal of neuroradiology AJNR, 34(4), pp. 740-6. Oak Brook, Ill.: American Society of Neuroradiology 10.3174/ajnr.A3307

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Early stratification of degenerative processes is a prerequisite to warrant therapeutic options in prodromal Alzheimer disease. Our aim was to investigate differences in cerebral macromolecular tissue composition between patients with AD, mild cognitive impairment, and age- and sex-matched healthy controls by using model-based magnetization transfer with a binary spin-bath magnetization transfer model and magnetization transfer ratio at 1.5 T.

Item Type:

Journal Article (Original Article)

Division/Institute:

04 Faculty of Medicine > Department of Radiology, Neuroradiology and Nuclear Medicine (DRNN) > Institute of Diagnostic and Interventional Neuroradiology
04 Faculty of Medicine > University Psychiatric Services > University Hospital of Psychiatry and Psychotherapy > Management

UniBE Contributor:

Wiest, Roland; Burren, Yuliya; Hauf, Martinus; Zbinden, Martin and Cattapan-Ludewig, Katja

ISSN:

0195-6108

Publisher:

American Society of Neuroradiology

Language:

English

Submitter:

Factscience Import

Date Deposited:

04 Oct 2013 14:30

Last Modified:

19 Mar 2014 14:27

Publisher DOI:

10.3174/ajnr.A3307

PubMed ID:

23064592

URI:

https://boris.unibe.ch/id/eprint/11574 (FactScience: 217776)

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