Heterogeneity in vaccination coverage explains the size and occurrence of measles epidemics in German surveillance data

Herzog, S A; Paul, M; Held, L (2011). Heterogeneity in vaccination coverage explains the size and occurrence of measles epidemics in German surveillance data. Epidemiology and infection, 139(4), pp. 505-515. Cambridge: Cambridge University Press 10.1017/S0950268810001664

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The objective of this study was to characterize empirically the association between vaccination coverage and the size and occurrence of measles epidemics in Germany. In order to achieve this we analysed data routinely collected by the Robert Koch Institute, which comprise the weekly number of reported measles cases at all ages as well as estimates of vaccination coverage at the average age of entry into the school system. Coverage levels within each federal state of Germany are incorporated into a multivariate time-series model for infectious disease counts, which captures occasional outbreaks by means of an autoregressive component. The observed incidence pattern of measles for all ages is best described by using the log proportion of unvaccinated school starters in the autoregressive component of the model.

Item Type:

Journal Article (Original Article)

Division/Institute:

04 Faculty of Medicine > Pre-clinic Human Medicine > Institute of Social and Preventive Medicine (ISPM)

UniBE Contributor:

Herzog, Sereina

ISSN:

0950-2688

Publisher:

Cambridge University Press

Language:

English

Submitter:

Factscience Import

Date Deposited:

04 Oct 2013 14:09

Last Modified:

05 Dec 2022 14:00

Publisher DOI:

10.1017/S0950268810001664

PubMed ID:

20619079

Web of Science ID:

000288225200003

BORIS DOI:

10.7892/boris.1160

URI:

https://boris.unibe.ch/id/eprint/1160 (FactScience: 202016)

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