Circadian elevation of IL-6 levels in Muckle-Wells syndrome: a disorder of the neuro-immune axis?

Gerbig, A. W.; Dahinden, C. A.; Mullis, P.; Hunziker, T. (1998). Circadian elevation of IL-6 levels in Muckle-Wells syndrome: a disorder of the neuro-immune axis? QJM - an international journal of medicine, 91(7), pp. 489-492. Oxford University Press 10.1093/qjmed/91.7.489

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Muckle-Wells syndrome (MWS) is a rare autosomal dominant hereditary disorder characterized by chronic recurrent urticaria, arthralgia, sensorineural deafness, and in some cases nephropathy due to amyloidosis (AA type). We report a 21-year-old woman and her father, both suffering from this syndrome, in whom elevated serum levels of IL-6 could be documented during the flares of urticaria, and discuss the relevance of this finding for MWS.

Item Type:

Journal Article (Further Contribution)

Division/Institute:

04 Faculty of Medicine > Department of Dermatology, Urology, Rheumatology, Nephrology, Osteoporosis (DURN) > Clinic of Dermatology
04 Faculty of Medicine > Department of Gynaecology, Paediatrics and Endocrinology (DFKE) > Clinic of Paediatric Medicine
04 Faculty of Medicine > Department of Haematology, Oncology, Infectious Diseases, Laboratory Medicine and Hospital Pharmacy (DOLS) > Institute for Immunology [discontinued]

UniBE Contributor:

Dahinden, Clemens A.; Mullis, Primus-Eugen and Hunziker, Thomas

Subjects:

600 Technology > 610 Medicine & health

ISSN:

1460-2725

Publisher:

Oxford University Press

Language:

English

Submitter:

Marceline Brodmann

Date Deposited:

23 Sep 2020 08:04

Last Modified:

23 Sep 2020 08:04

Publisher DOI:

10.1093/qjmed/91.7.489

BORIS DOI:

10.7892/boris.116081

URI:

https://boris.unibe.ch/id/eprint/116081

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