PSMA-PET based radiotherapy: a review of initial experiences, survey on current practice and future perspectives.

Zschaeck, Sebastian; Lohaus, Fabian; Beck, Marcus; Habl, Gregor; Kroeze, Stephanie; Zamboglou, Constantinos; Koerber, Stefan Alexander; Debus, Jürgen; Hölscher, Tobias; Wust, Peter; Ganswindt, Ute; Baur, Alexander D J; Zöphel, Klaus; Cihoric, Nikola; Guckenberger, Matthias; Combs, Stephanie E; Grosu, Anca Ligia; Ghadjar, Pirus; Belka, Claus (2018). PSMA-PET based radiotherapy: a review of initial experiences, survey on current practice and future perspectives. Radiation oncology, 13(1), p. 90. BioMed Central 10.1186/s13014-018-1047-5

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Gallium prostate specific membrane antigen (PSMA) ligand positron emission tomography (PET) is an increasingly used imaging modality in prostate cancer, especially in cases of tumor recurrence after curative intended therapy. Owed to the novelty of the PSMA-targeting tracers, clinical evidence on the value of PSMA-PET is moderate but rapidly increasing. State of the art imaging is pivotal for radiotherapy treatment planning as it may affect dose prescription, target delineation and use of concomitant therapy.This review summarizes the evidence on PSMA-PET imaging from a radiation oncologist's point of view. Additionally a short survey containing twelve examples of patients and 6 additional questions was performed in seven mayor academic centers with experience in PSMA ligand imaging and the findings are reported here.

Item Type:

Journal Article (Review Article)

Division/Institute:

04 Faculty of Medicine > Department of Haematology, Oncology, Infectious Diseases, Laboratory Medicine and Hospital Pharmacy (DOLS) > Clinic of Radiation Oncology

UniBE Contributor:

Cihoric, Nikola and Ghadjar, Pirus

Subjects:

600 Technology > 610 Medicine & health

ISSN:

1748-717X

Publisher:

BioMed Central

Language:

English

Submitter:

Beatrice Scheidegger

Date Deposited:

21 Jun 2018 15:48

Last Modified:

28 Nov 2020 02:28

Publisher DOI:

10.1186/s13014-018-1047-5

PubMed ID:

29751842

Uncontrolled Keywords:

Image guided treatment planning PSMA-PET Primary radiotherapy Prostate-cancer Review Salvage radiotherapy Survey

BORIS DOI:

10.7892/boris.116520

URI:

https://boris.unibe.ch/id/eprint/116520

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