Fecal strongyle egg counts in horses with suspected pre-clinical pituitary pars intermedia dysfunction before and after treatment with pergolide.

Christen, Garance Anne; Gerber, Vinzenz; van der Kolk, Johannes Hermanus; Frey, Caroline Franziska; Fouché, Nathalie Elisa (2018). Fecal strongyle egg counts in horses with suspected pre-clinical pituitary pars intermedia dysfunction before and after treatment with pergolide. Veterinary journal, 235, pp. 60-62. Elsevier 10.1016/j.tvjl.2018.03.007

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Pituitary pars intermedia dysfunction (PPID) has been associated with diminished immune response in aged horses. This prospective study hypothesised that this may result in increased strongyle egg shedding in affected animals and that horses treated with pergolide would have reduced fecal egg counts (eggs per gram, EPG) compared to placebo-treated animals. Adrenocorticotropic hormone (ACTH) concentrations and EPG were tested in 48 horses. There were no significant differences in baseline EPG between horses with pre-clinical PPID and healthy controls. There was no significant difference in EPG between horses with PPID after treatment with pergolide and placebo-treated animals. Using EPG as a marker of immune function, these results did not support a proposed decrease in immune function in horses with pre-clinical PPID.

Item Type:

Journal Article (Original Article)

Division/Institute:

05 Veterinary Medicine > Department of Clinical Veterinary Medicine (DKV) > Equine Clinic
05 Veterinary Medicine > Department of Clinical Veterinary Medicine (DKV)

UniBE Contributor:

Christen, Garance Anne; Gerber, Vinzenz and Fouché, Nathalie Elisa

Subjects:

600 Technology > 630 Agriculture

ISSN:

1090-0233

Publisher:

Elsevier

Language:

English

Submitter:

Andrea Gassmann-Suter

Date Deposited:

18 Jun 2018 07:02

Last Modified:

01 Jun 2019 02:31

Publisher DOI:

10.1016/j.tvjl.2018.03.007

PubMed ID:

29704940

Uncontrolled Keywords:

Equine Geriatric PPID Parasites Placebo

BORIS DOI:

10.7892/boris.117225

URI:

https://boris.unibe.ch/id/eprint/117225

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