Rodent-free cyclical transmission of Trypanosoma brucei brucei.

Naguleswaran, Arunasalam; Roditi, Isabel (2017). Rodent-free cyclical transmission of Trypanosoma brucei brucei. Molecular and biochemical parasitology, 217, pp. 16-18. Elsevier 10.1016/j.molbiopara.2017.08.005

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We provide a simple protocol enabling cyclical transmission of Trypanosoma brucei brucei to be performed without the need for mammals. These procedures have two advantages: they are in line with 3R principles of animal use - replace, refine, reduce - and may enable more laboratories to study the complete life cycle.

Item Type:

Journal Article (Original Article)

Division/Institute:

08 Faculty of Science > Department of Biology > Institute of Cell Biology

UniBE Contributor:

Naguleswaran, Arunasalam and Roditi, Isabel

Subjects:

500 Science > 570 Life sciences; biology

ISSN:

0166-6851

Publisher:

Elsevier

Funders:

[UNSPECIFIED] Howard Hughes Medical Institute
[UNSPECIFIED] Canton of Bern

Language:

English

Submitter:

Isabel Roditi

Date Deposited:

09 Jul 2018 17:08

Last Modified:

23 Oct 2019 15:24

Publisher DOI:

10.1016/j.molbiopara.2017.08.005

PubMed ID:

28843782

Uncontrolled Keywords:

3R concept Animal replacement Metacyclic forms Salivary glands Trypanosome Tsetse

BORIS DOI:

10.7892/boris.117301

URI:

https://boris.unibe.ch/id/eprint/117301

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