Extensive radical surgery as therapeutic principal in patients with pancreatic carcinoma

Baer, H. U.; Läuffer, J. M.; Sadowski, Ch.; Büchler, Markus Wolfgang (1997). Extensive radical surgery as therapeutic principal in patients with pancreatic carcinoma. Acta Chirurgica Austriaca, 29(5), pp. 267-270. Springer-Verlag 10.1007/BF02621319

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Background: The classical and pylorus-preserving Whipple procedure in patients with pancreatic carcinoma can be performed safely with low morbidity and mortality. Therefore, the indication for surgical intervention should be indicated with less restrictions. Methods: It has been shown that even a palliative resectional procedure has advantages for the patients. Prerequisite to experienced surgeons should be 10 pancreatic resections per year and a mortality < 10%. In order to reduce postoperative typical complications after pancreatic resections in the perioperative period beside antibiotics Octreotid has to be given to inhibit exocrine pancreatic secretion. Results: Within 32 months 113 patients with pancreatic cancer were treated at out hospital. Resection rate was 50% (57/113), in the majority of patients a pylorus-preserving whipple procedure was performed (30/57). Postoperative morbidity was 22.3%, no patient died. Conclusions: The value of extensive and radical pancreatoduodenectomy and the reconstruction according to classical and the pylorus-preserving procedure as well as the role of adjuvant or neoadjuvant chemo- and/or radiotherapy have to be proven in randomized controlled trials. Pancreatic cancer is still a challenging disease for researchers to improve patient’s prognosis.

Item Type:

Journal Article (Original Article)

Division/Institute:

04 Faculty of Medicine > Department of Gastro-intestinal, Liver and Lung Disorders (DMLL) > Clinic of Visceral Surgery and Medicine > Visceral Surgery

UniBE Contributor:

Büchler, Markus Wolfgang

ISSN:

0001-544X

Publisher:

Springer-Verlag

Language:

German

Submitter:

Markus Müller

Date Deposited:

10 Jul 2018 15:36

Last Modified:

26 Jul 2018 14:30

Publisher DOI:

10.1007/BF02621319

BORIS DOI:

10.7892/boris.117890

URI:

https://boris.unibe.ch/id/eprint/117890

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