Estimating lifetime and 10-year risk of lung cancer.

Bruder, Christina; Bulliard, Jean-Luc; Germann, Simon; Konzelmann, Isabelle; Bochud, Murielle; Leyvraz, Magali; Chiolero, Arnaud (2018). Estimating lifetime and 10-year risk of lung cancer. Preventive Medicine Reports, 11, pp. 125-130. Elsevier 10.1016/j.pmedr.2018.06.010

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Lung cancer is the commonest cancer worldwide. Mortality and incidence rates are traditionally used to assess cancer burden and as public health indicators. However, these metrics are difficult to interpret at an individual level. Providing the lifetime and 10-year risks of cancer could improve risk communication. Our aim was to estimate current lifetime and 10-year risks of lung cancer by smoking status and changes in these risks between 1995 and 2013 in a Swiss population. We used all lung cancer cases recorded between 1995 and 2013 by two population-based cancer registries in the contiguous cantons of Vaud and Valais, in Western Switzerland. We estimated sex-specific lifetime risk and 10-year risk of lung cancer using the current probability method, accounting for competing risk of death. Estimates were also provided by smoking status. Between 1995 and 2013, 9623 cases of lung cancer were recorded. During this period, the lifetime risk decreased in men from 7.1% to 6.7% and increased in women from 2.5% to 4.1%. In both sexes, the 10-year risk of lung cancer increased with age until the age of 60-70 and decreased thereafter. Difference in the cumulative risk between current, former, and never smokers were very large and reported in user-friendly charts to ease risk communication. These lifetime and 10-year risk estimates could be used systematically as public health indicators. Regularly updating risk estimations are necessary for conditions like lung cancer whose incidence has changed substantially.

Item Type:

Journal Article (Original Article)

Division/Institute:

04 Faculty of Medicine > Medical Education > Institute of General Practice and Primary Care (BIHAM)

UniBE Contributor:

Chiolero, Arnaud

Subjects:

600 Technology > 610 Medicine & health
300 Social sciences, sociology & anthropology > 360 Social problems & social services

ISSN:

2211-3355

Publisher:

Elsevier

Language:

English

Submitter:

Doris Kopp Heim

Date Deposited:

05 Jul 2018 16:41

Last Modified:

26 May 2020 15:51

Publisher DOI:

10.1016/j.pmedr.2018.06.010

PubMed ID:

29942733

Uncontrolled Keywords:

Lifetime risk Lung cancer Public health indicator Risk communication Switzerland

BORIS DOI:

10.7892/boris.118343

URI:

https://boris.unibe.ch/id/eprint/118343

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