Schoepfer, Alain M; Straumann, Alex; Safroneeva, Ekaterina (2018). Pharmacologic Treatment of Eosinophilic Esophagitis: An Update. Gastrointestinal Endoscopy Clinics of North America, 28(1), pp. 77-88. Elsevier 10.1016/j.giec.2017.07.007
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Eosinophilic esophagitis (EoE) is defined as a chronic, immune-medicated or antigen-mediated, esophageal disease, characterized clinically by symptoms related to esophageal dysfunction and histologically by eosinophil-predominant inflammation. Food allergens are identified in most patients. Treatment strategies include elimination diets, drugs, and esophageal dilation. This article focuses on pharmacologic treatment. Currently, there is no pharmacologic treatment that has been approved by regulatory authorities. Established pharmacologic options to treat EoE include proton pump inhibitors and swallowed topical steroids. Several biologic therapies are currently under evaluation and some of them have shown promising results in improving biologic endpoints and patient-reported outcomes.
Item Type: |
Journal Article (Review Article) |
|---|---|
Division/Institute: |
04 Faculty of Medicine > Pre-clinic Human Medicine > Institute of Social and Preventive Medicine (ISPM) |
UniBE Contributor: |
Safroneeva, Ekaterina |
Subjects: |
600 Technology > 610 Medicine & health 300 Social sciences, sociology & anthropology > 360 Social problems & social services |
ISSN: |
1052-5157 |
Publisher: |
Elsevier |
Language: |
English |
Submitter: |
Tanya Karrer |
Date Deposited: |
19 Jul 2018 13:48 |
Last Modified: |
05 Dec 2022 15:16 |
Publisher DOI: |
10.1016/j.giec.2017.07.007 |
PubMed ID: |
29129301 |
Uncontrolled Keywords: |
Biologic therapy Budesonide Eosinophilic esophagitis Fluticasone Pharmacologic treatment Proton pump inhibitors |
BORIS DOI: |
10.7892/boris.118552 |
URI: |
https://boris.unibe.ch/id/eprint/118552 |
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