14-3-3 proteins in Echinococcus: their role and potential as protective antigens.

Siles-Lucas, Mar; Merli, Michael; Gottstein, Bruno (2008). 14-3-3 proteins in Echinococcus: their role and potential as protective antigens. Experimental parasitology, 119(4), pp. 516-523. Elsevier 10.1016/j.exppara.2008.01.009

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14-3-3 Proteins are a family of highly conserved proteins among all eukaryotic organisms studied so far. As basically intracellular proteins, they play a key role in basic cellular events related to cellular proliferation, including signal transduction, cell-cycle control, cell differentiation and cell survival. The 14-3-3 proteins have been described and characterized in several parasites, and mostly studied in Echinococcus granulosus and Echinococcus multilocularis. Here, we review the discoveries regarding this protein family in the genus Echinococcus, describing new data about specific aspects related with their implication in the parasite biology and immunology in the frame of the host-parasite relationship.

Item Type:

Journal Article (Review Article)

Division/Institute:

05 Veterinary Medicine > Department of Infectious Diseases and Pathobiology (DIP) > Institute of Parasitology

UniBE Contributor:

Gottstein, Bruno

Subjects:

600 Technology > 610 Medicine & health
600 Technology > 630 Agriculture

ISSN:

0014-4894

Publisher:

Elsevier

Language:

English

Submitter:

Bruno Gottstein

Date Deposited:

23 Jul 2018 08:47

Last Modified:

23 Jul 2018 08:47

Publisher DOI:

10.1016/j.exppara.2008.01.009

PubMed ID:

18316081

BORIS DOI:

10.7892/boris.118872

URI:

https://boris.unibe.ch/id/eprint/118872

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