Challenges for diagnosis and control of cystic hydatid disease.

Barnes, T S; Deplazes, P; Gottstein, Bruno; Jenkins, D J; Mathis, A; Siles-Lucas, M; Torgerson, P R; Ziadinov, I; Heath, D D (2012). Challenges for diagnosis and control of cystic hydatid disease. Acta tropica, 123(1), pp. 1-7. Elsevier 10.1016/j.actatropica.2012.02.066

[img] Text
1-s2.0-S0001706X12001349-main.pdf - Published Version
Restricted to registered users only
Available under License Publisher holds Copyright.

Download (381kB) | Request a copy

This paper is based on the experience of the authors, with the aim to define the challenges for Echinococcus granulosus (E.g./CE) diagnosis and control for those countries that may now or in the future be contemplating control of hydatid disease. A variety of methods are available for diagnosis in humans but a universal gold standard is lacking. Diagnosis in definitive hosts can avoid necropsy by the use of methods such as coproantigen detection but test performance is variable between populations. A sylvatic cycle adds challenges in some countries and the epidemiology of the parasite in these hosts is poorly understood. Control by solely administering praziquantel to dogs is not effective in developing countries where the disease is endemic. Additional avenues to pursue include the instigation of participatory planning, use of an existing vaccination for intermediate hosts and development of a vaccine and long-acting anthelmitic implants for definitive hosts. Promoting public acceptance of control of the dog population by humane euthanasia and reduced reproduction is also essential.

Item Type:

Journal Article (Review Article)

Division/Institute:

05 Veterinary Medicine > Research Foci > Host-Pathogen Interaction
05 Veterinary Medicine > Department of Infectious Diseases and Pathobiology (DIP) > Institute of Parasitology

UniBE Contributor:

Gottstein, Bruno

Subjects:

600 Technology > 610 Medicine & health
600 Technology > 630 Agriculture

ISSN:

0001-706X

Publisher:

Elsevier

Language:

English

Submitter:

Bruno Gottstein

Date Deposited:

23 Jul 2018 08:33

Last Modified:

23 Jul 2018 08:33

Publisher DOI:

10.1016/j.actatropica.2012.02.066

PubMed ID:

22410539

BORIS DOI:

10.7892/boris.118901

URI:

https://boris.unibe.ch/id/eprint/118901

Actions (login required)

Edit item Edit item
Provide Feedback