Challenges for diagnosis and control of cystic hydatid disease.

Barnes, T S; Deplazes, P; Gottstein, Bruno; Jenkins, D J; Mathis, A; Siles-Lucas, M; Torgerson, P R; Ziadinov, I; Heath, D D (2012). Challenges for diagnosis and control of cystic hydatid disease. Acta tropica, 123(1), pp. 1-7. Elsevier 10.1016/j.actatropica.2012.02.066

Text 1-s2.0-S0001706X12001349-main.pdf - Published Version Restricted to registered users only Available under License Publisher holds Copyright. Download (381kB) | Request a copy

This paper is based on the experience of the authors, with the aim to define the challenges for Echinococcus granulosus (E.g./CE) diagnosis and control for those countries that may now or in the future be contemplating control of hydatid disease. A variety of methods are available for diagnosis in humans but a universal gold standard is lacking. Diagnosis in definitive hosts can avoid necropsy by the use of methods such as coproantigen detection but test performance is variable between populations. A sylvatic cycle adds challenges in some countries and the epidemiology of the parasite in these hosts is poorly understood. Control by solely administering praziquantel to dogs is not effective in developing countries where the disease is endemic. Additional avenues to pursue include the instigation of participatory planning, use of an existing vaccination for intermediate hosts and development of a vaccine and long-acting anthelmitic implants for definitive hosts. Promoting public acceptance of control of the dog population by humane euthanasia and reduced reproduction is also essential.

Interest & Impact

Downloads

0 since deposited on 23 Jul 2018
0 in the past 12 months

Citations

5 Citations in Web of Science ®
6 Citations in Scopus

Search

in Google Scholar™

Services

Actions (login required)

Edit item

Actions (login required)

Edit item