Biochemical mechanisms implemented by human acute myeloid leukemia cells to suppress host immune surveillance

Yasinska, Inna M.; Gonçalves Silva, Isabel; Sakhnevych, Svetlana; Gibbs, Bernhard F.; Raap, Ulrike; Fasler-Kan, Elizaveta; Sumbayev, Vadim V. (2018). Biochemical mechanisms implemented by human acute myeloid leukemia cells to suppress host immune surveillance. Cellular & molecular immunology, 15(11), pp. 989-991. Nature Publ. Group 10.1038/s41423-018-0047-6

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Acute myeloid leukaemia (AML) is a blood/bone marrow cancer originating from myeloid cell precusors capable of self-renewing. AML cells implement biochemical mechanisms which allow them not only to survive, but also to successfully escape immune surveillance. ln this work, we discuss crucial molecular mechanisms used by human AML cells in order to evade immune attack.

Item Type:

Journal Article (Further Contribution)

Division/Institute:

04 Faculty of Medicine > Department of Gynaecology, Paediatrics and Endocrinology (DFKE) > Clinic of Paediatric Surgery
04 Faculty of Medicine > Pre-clinic Human Medicine > BioMedical Research (DBMR) > Unit Childrens Hospital > Research Group Pediatric Surgery

UniBE Contributor:

Fasler-Kan, Elizaveta

Subjects:

600 Technology > 610 Medicine & health

ISSN:

1672-7681

Publisher:

Nature Publ. Group

Language:

English

Submitter:

Christoph Steffen

Date Deposited:

26 Nov 2018 10:50

Last Modified:

05 Dec 2022 15:17

Publisher DOI:

10.1038/s41423-018-0047-6

PubMed ID:

29872115

URI:

https://boris.unibe.ch/id/eprint/119582

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