Meningitis caused by Mycoplasma mycoides subspecies capri in a goat

Schumacher, V.L.; Hinckley, L.; Liao, X.; Tulman, E.; Geary, S.J.; Smyth, J.A. (2011). Meningitis caused by Mycoplasma mycoides subspecies capri in a goat. Journal of veterinary diagnostic investigation, 23(3), pp. 565-9. Columbia, Mo.: American Association of Veterinary Laboratory Diagnosticians AAVLD 10.1177/1040638711403413

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A 2-year-old, female goat from Connecticut was submitted for necropsy with a 5-day history of pyrexia and intermittent neurologic signs, including nystagmus, seizures, and circling. Postmortem examination revealed suppurative meningitis. Histologic examination of the brain revealed that the meninges were diffusely infiltrated by moderate numbers of lymphocytes, macrophages, and fibrin, with scattered foci of dense neutrophilic infiltrate. Culture of pus and brainstem yielded typical mycoplasma colonies. DNA sequencing of the 16S ribosomal RNA gene revealed 99% sequence homology with Mycoplasma mycoides subspecies capri and Mycoplasma mycoides subspecies mycoides Large Colony biotype, which are genetically indistinguishable and likely to be combined as a single subspecies labeled M. mycoides subsp. capri. The present case is unusual in that not only are mycoplasma an uncommon cause of meningitis in animals, but additionally, in that all other reported cases of mycoplasma meningitis in goats, systemic lesions were also present. In the present case, meningitis was the only lesion, thus illustrating the need to consider mycoplasma as a differential diagnosis for meningitis in goats.

Item Type:

Journal Article (Original Article)


05 Veterinary Medicine > Department of Infectious Diseases and Pathobiology (DIP) > Institute of Animal Pathology

UniBE Contributor:

Schumacher, Vanessa




American Association of Veterinary Laboratory Diagnosticians AAVLD




Factscience Import

Date Deposited:

04 Oct 2013 14:31

Last Modified:

05 Dec 2022 14:10

Publisher DOI:


Web of Science ID:


URI: (FactScience: 218282)

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