A simple table based on height to assess elevated and high blood pressure in children.

Zhang, Yuanyuan; Yang, Liu; Hou, Yaping; Zhao, Min; Chiolero, Arnaud; Bovet, Pascal; Xi, Bo (2019). A simple table based on height to assess elevated and high blood pressure in children. Journal of human hypertension, 33(3), pp. 248-254. Nature Publishing Group 10.1038/s41371-018-0128-0

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The 2017 American Academy of Pediatrics (AAP) guideline for assessing "elevated blood pressure (BP) (90 BP percentile)" and "high BP (95 BP percentile)" includes a large number of BP cut-offs based on sex, age and height, which makes it cumbersome to use in clinical practice. We developed and evaluated the performance of a simple table based on a child's height only to assess elevated and high BP in children compared to the reference AAP guideline based on sex, age and height. Data came from 6816 children aged 8-12 years from the U.S. National Health and Nutrition Examination Survey (NHANES) 1999-2016 and 3145 participants aged 5-12 years from NHANES III (1988-1994). Compared to the reference AAP guideline, the simple table had high values of AUC (0.96/0.91), sensitivity (92.7%/83.2%), specificity (99.0%/99.4%), PPV (92.6%/89.3%), NPV (99.0%/99.0%), and Kappa coefficient (0.92/0.85) for screening elevated/high BP when applied to NHANES, and values were similarly high when applied to NHANES III. These findings show that the simple table based on height only performed nearly as well as the reference 2017 AAP guideline based on sex, age and height for assessing elevated and high BP in U.S. children. This simple table may be a useful screening tool to assess high BP in children aged 5-12 years, particularly in a context of mass screening programs.

Item Type:

Journal Article (Original Article)

Division/Institute:

04 Faculty of Medicine > Medical Education > Institute of General Practice and Primary Care (BIHAM)

UniBE Contributor:

Chiolero, Arnaud

Subjects:

600 Technology > 610 Medicine & health
300 Social sciences, sociology & anthropology > 360 Social problems & social services

ISSN:

0950-9240

Publisher:

Nature Publishing Group

Language:

English

Submitter:

Doris Kopp Heim

Date Deposited:

20 Nov 2018 15:27

Last Modified:

21 Nov 2019 04:09

Publisher DOI:

10.1038/s41371-018-0128-0

PubMed ID:

30401980

BORIS DOI:

10.7892/boris.121419

URI:

https://boris.unibe.ch/id/eprint/121419

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