Diurnal pattern of melatonin in blood and milk of dairy Cows

Castro, N.; Spengler, M.; Lollivier, V.; Wellnitz, O.; Meyer, H.H.D.; Bruckmaier, R.M. (2011). Diurnal pattern of melatonin in blood and milk of dairy Cows. Milchwissenschaft, 66(4), pp. 352-353. Kempten: AVA Agrar-Verlag Allgäu

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The aim of the present study was to evaluate the diurnal rhythm of melatonin concentration in blood and milk of dairy cows. Blood was sampled and the entire milk was removed every hour and melatonin concentration was measured throughout 24 hours in June in 12 dairy cows (around 16 hours daylight). Both, blood plasma and milk melatonin concentration showed a diurnal pattern with high levels during scotoperiod and low levels during photoperiod. Average blood plasma melatonin was 16.2 +/- 2.3 pg/mL during the photoperiod (0800-2200h), started to increase at 2100h, and reached a plateau at 2300h (16.0 +/- 4.4 pg/mL). Peak concentration was reached at 0100h (25.4 +/- 5.6 pg/mL). At 0700h melatonin decreased to baseline level again. The melatonin pattern in milk paralleled the pattern in blood. However, the concentration of melatonin was much lower in milk than in blood with a maximum concentration of 2.9 +/- 0.6 pg/mL at all tested time points.

Item Type:

Journal Article (Original Article)


05 Veterinary Medicine > Department of Clinical Research and Veterinary Public Health (DCR-VPH) > Veterinary Physiology

UniBE Contributor:

Wellnitz, Olga and Bruckmaier, Rupert




AVA Agrar-Verlag Allgäu




Factscience Import

Date Deposited:

04 Oct 2013 14:31

Last Modified:

21 Jan 2014 15:04

Web of Science ID:



https://boris.unibe.ch/id/eprint/12147 (FactScience: 218435)

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