Age at start of endurance training is associated with patterns of left ventricular hypertrophy in middle-aged runners.

Ryffel, Christoph Philippe; Eser, Prisca; Trachsel, Lukas; Brugger, Nicolas Jacques; Wilhelm, Matthias (2018). Age at start of endurance training is associated with patterns of left ventricular hypertrophy in middle-aged runners. International journal of cardiology, 267, pp. 133-138. Elsevier 10.1016/j.ijcard.2018.04.111

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BACKGROUND Left ventricular hypertrophy (LVH) is a physiological adaptation to long-term endurance training. We investigated the impact of age at start of endurance training on LV geometry in a cohort of male, middle-aged, non-elite endurance athletes. METHODS A total of 121 healthy, normotensive, Caucasian participants of a 10-mile race were recruited and assessed with an echocardiogram and a comprehensive interview. Athletes were classified based on patterns of LVH. RESULTS Thirty-five athletes (31%) had LVH. Athletes with eccentric LVH (16%) were significantly younger at start of endurance training compared to athletes with concentric LVH (15%, 14 ± 5 years vs. 31 ± 8 years; P < 0.001). Although the yearly volume of endurance training was comparable between athletes with eccentric and concentric LVH, athletes with eccentric LVH had shorter race times. All athletes with an increased LV end diastolic volume index (LVEDVI; ≥74 ml/m) started endurance training before or at age 25. CONCLUSIONS In our cohort of non-elite middle-aged runners, eccentric LVH was found only in athletes with an early start of endurance training. In case of a mature starting age, endurance training may, contrary to what is commonly assumed, also lead to concentric LVH. The consideration of endurance training starting age may lead to a better understanding of morphological adaptations of the heart.

Item Type:

Journal Article (Original Article)

Division/Institute:

04 Faculty of Medicine > Department of Cardiovascular Disorders (DHGE) > Clinic of Cardiology

UniBE Contributor:

Ryffel, Christoph Philippe; Eser, Prisca; Trachsel, Lukas; Brugger, Nicolas Jacques and Wilhelm, Matthias

Subjects:

600 Technology > 610 Medicine & health

ISSN:

0167-5273

Publisher:

Elsevier

Language:

English

Submitter:

Michelle Dysli

Date Deposited:

08 Feb 2019 14:59

Last Modified:

05 Dec 2019 06:32

Publisher DOI:

10.1016/j.ijcard.2018.04.111

PubMed ID:

29957253

Uncontrolled Keywords:

Exercise training Left ventricular hypertrophy Left ventricular mass

BORIS DOI:

10.7892/boris.121848

URI:

https://boris.unibe.ch/id/eprint/121848

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