Jafari, Morteza; Knüsel, Evelyne; Cazzaniga, Simone; Hunger, Robert (2018). A Retrospective Cohort Study on Patients with Hidradenitis Suppurativa. Dermatology, 234(1-2), pp. 71-78. Karger 10.1159/000488344
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BACKGROUND
Hidradenitis suppurativa (HS) is one of the most distressing conditions observed in dermatology and has a substantial negative effect on the quality of life of affected persons.
OBJECTIVES
The aim of this study was to evaluate different treatment strategies in patients with HS.
METHODS
In a retrospective cohort, all patients with HS (July 2015 to March 2017) were reviewed. Collected data consisted of patients' demographics, clinical characteristics, psychosocial situation, and previous and current treatments. In addition, therapy response to the most recent prescribed treatments was assessed.
RESULTS
102 patients (38 females, 64 males; median age 37.5 years) were included in this study. 68.4% of patients had BMI ≥25, and 76.5% of patients were current smokers. Hurley stages I, II, and III were detected in 13.5, 53.1, and 33.3% of patients, respectively. The most commonly administered treatments were surgery (67.6%), nonantibiotic topical therapies (72.5%), antibiotic topical therapies (55.9%), systemic antibiotics (88.2%), and biologics in 11.8% of the patients. 84.6% of the patients showed a response (27.5 and 47.1% partial and complete response, respectively) to the treatments.
CONCLUSION
HS as a chronic, recurrent inflammatory skin disease is associated with smoking and obesity. Application of systemic antibiotics is the most frequent treatment strategy for this disease. However, surgical intervention seems to be the most effective treatment strategy.
Item Type: |
Journal Article (Original Article) |
|---|---|
Division/Institute: |
04 Faculty of Medicine > Department of Dermatology, Urology, Rheumatology, Nephrology, Osteoporosis (DURN) > Clinic of Dermatology |
UniBE Contributor: |
Jafari, Morteza, Cazzaniga, Simone, Hunger, Robert |
Subjects: |
600 Technology > 610 Medicine & health |
ISSN: |
1018-8665 |
Publisher: |
Karger |
Language: |
English |
Submitter: |
Andrea Studer-Gauch |
Date Deposited: |
07 Dec 2018 09:20 |
Last Modified: |
15 Jun 2023 12:41 |
Publisher DOI: |
10.1159/000488344 |
PubMed ID: |
29758553 |
Uncontrolled Keywords: |
Hidradenitis suppurativa Quality of life Treatment |
BORIS DOI: |
10.48350/121886 |
URI: |
https://boris.unibe.ch/id/eprint/121886 |
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