The Swiss Paediatric Airway Cohort (SPAC) [protocol].

Pedersen, Eva S L; de Jong, Carmen C M; Ardura Garcia, Cristina; Barben, Juerg; Casaulta, Carmen; Frey, Urs; Jochmann, Anja; Latzin, Philipp; Moeller, Alexander; Regamey, Nicolas; Singer, Florian; Spycher, Ben; Sutter, Oliver; Goutaki, Myrofora; Kuehni, Claudia E (2018). The Swiss Paediatric Airway Cohort (SPAC) [protocol]. ERJ Open Research, 4(4), 00050. European Respiratory Society 10.1183/23120541.00050-2018

[img]
Preview
Text
Pedersen ERJOpenRes 2018.pdf - Published Version
Available under License Creative Commons: Attribution-Noncommercial (CC-BY-NC).

Download (707kB) | Preview

Chronic respiratory symptoms, such as cough, wheeze and dyspnoea, are common in children; however, most research has, with the exception of a few large-scale clinical cohort studies, been performed in the general population or in small, highly-selected samples. The Swiss Paediatric Airway Cohort (SPAC) is a national, prospective clinical cohort of children and adolescents who visit physicians for recurrent conditions, such as wheeze and cough, and exercise-related respiratory problems. The SPAC is an observational study and baseline assessment includes standardised questionnaires for families and data extracted from hospital records, including results of clinically indicated investigations, diagnoses and treatments. Outcomes are assessed through annual questionnaires, monthly symptom reporting mobile phone and follow-up visits. The SPAC will address important questions about clinical phenotypes, diagnosis, treatment, and the short- and long-term prognosis of common respiratory problems in children. The cohort currently consists of 347 patients from four major hospitals (Bern, Zurich, Basel and Lucerne), with 70-80 additional patients joining each month. More centres will join and the target sample size is a minimum of 3000 patients. The SPAC will provide real-life data on children visiting the Swiss healthcare system for common respiratory problems and will provide a research platform for health services research and nested clinical and translational studies.

Item Type:

Journal Article (Further Contribution)

Division/Institute:

04 Faculty of Medicine > Department of Gynaecology, Paediatrics and Endocrinology (DFKE) > Clinic of Paediatric Medicine
04 Faculty of Medicine > Pre-clinic Human Medicine > Institute of Social and Preventive Medicine (ISPM)

Graduate School:

Graduate School for Cellular and Biomedical Sciences (GCB)
Graduate School for Health Sciences (GHS)

UniBE Contributor:

Pedersen, Eva Sophie Lunde, de Jong, Carmen Cornelia Maria, Ardura Garcia, Cristina, Casaulta, Carmen, Latzin, Philipp, Singer, Florian, Spycher, Ben, Goutaki, Myrofora, Kühni, Claudia

Subjects:

600 Technology > 610 Medicine & health
300 Social sciences, sociology & anthropology > 360 Social problems & social services

ISSN:

2312-0541

Publisher:

European Respiratory Society

Language:

English

Submitter:

Anette van Dorland

Date Deposited:

30 Nov 2018 11:18

Last Modified:

05 Dec 2022 15:21

Publisher DOI:

10.1183/23120541.00050-2018

PubMed ID:

30474037

Additional Information:

Pedersen and de Jong contributed equally to this work.

BORIS DOI:

10.7892/boris.121893

URI:

https://boris.unibe.ch/id/eprint/121893

Actions (login required)

Edit item Edit item
Provide Feedback