Segregation analysis of overweight body condition in an experimental cat population

Haring, T.; Wichert, B.; Dolf, G.; Haase, B. (2011). Segregation analysis of overweight body condition in an experimental cat population. Journal of heredity, 102(Suppl 1), S28-S31. Oxford: Oxford University Press 10.1093/jhered/esr029

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The goal of this study was to analyze the mode of inheritance of an overweight body condition in an experimental cat population. The cat population consisted of 95 cats of which 81 cats could be clearly classified into lean or overweight using the body condition scoring system according to Laflamme. The lean or overweight classification was then used for segregation analyses. Complex segregation analyses were employed to test for the significance of one environmental and 4 genetic models (general, mixed inheritance, major gene, and polygene). The general genetic model fit the data significantly better than the environmental model (P </= 0.0013). Among all other models employed, the major gene model explained the segregation of the overweight phenotype best. This is the first study in which a genetic component could be shown to be responsible for the development of overweight in cats.

Item Type:

Journal Article (Original Article)

Division/Institute:

05 Veterinary Medicine > Department of Clinical Research and Veterinary Public Health (DCR-VPH) > Institute of Genetics

UniBE Contributor:

Dolf, Gaudenz and Haase, Bianca

ISSN:

0022-1503

Publisher:

Oxford University Press

Language:

English

Submitter:

Factscience Import

Date Deposited:

04 Oct 2013 14:32

Last Modified:

27 Apr 2018 08:42

Publisher DOI:

10.1093/jhered/esr029

Web of Science ID:

000294370500005

BORIS DOI:

10.7892/boris.12269

URI:

https://boris.unibe.ch/id/eprint/12269 (FactScience: 218585)

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