Boilevin, Jérémy M.; Reymond, Jean-Louis (2018). Synthesis of Lipid-Linked Oligosaccharides (LLOs) and Their Phosphonate Analogues as Probes To Study Protein Glycosylation Enzymes. Synthesis - journal of synthetic organic chemistry, 50(14), pp. 2631-2654. Thieme 10.1055/s-0037-1609735
![[img]](https://boris.unibe.ch/style/images/fileicons/text.png) |
Text
s-0037-1609735.pdf - Published Version Restricted to registered users only Available under License Publisher holds Copyright. Download (2MB) |
Here we review chemical and chemoenzymatic methods for the synthesis of lipid-linked oligosaccharides (LLOs) and their phosphonate analogues, which serve as substrates and inhibitors to investigate the structure and mechanism of protein N-glycosylation enzymes. We emphasize how to overcome the challenges pertaining to the instability and difficult physicochemical properties of this class of compounds.
Item Type: |
Journal Article (Review Article) |
|---|---|
Division/Institute: |
08 Faculty of Science > Department of Chemistry, Biochemistry and Pharmaceutical Sciences (DCBP) |
UniBE Contributor: |
Boilevin, Jérémy Mathias, Reymond, Jean-Louis |
Subjects: |
500 Science > 570 Life sciences; biology 500 Science > 540 Chemistry |
ISSN: |
0039-7881 |
Publisher: |
Thieme |
Language: |
English |
Submitter: |
Sandra Tanja Zbinden Di Biase |
Date Deposited: |
19 Dec 2018 14:24 |
Last Modified: |
05 Dec 2022 15:23 |
Publisher DOI: |
10.1055/s-0037-1609735 |
BORIS DOI: |
10.7892/boris.122700 |
URI: |
https://boris.unibe.ch/id/eprint/122700 |
Actions (login required)
 |
Edit item |