Optical coherence tomography angiography findings in cystoid macular degeneration associated with central serous chorioretinopathy.

Sahoo, Niroj Kumar; Mishra, Sai Bhakti; Iovino, Claudio; Singh, Sumit Randhir; Munk, Marion; Berger, Lieselotte Erika; Peiretti, Enrico; Chhablani, Jay (2019). Optical coherence tomography angiography findings in cystoid macular degeneration associated with central serous chorioretinopathy. The British journal of ophthalmology, 103(11), pp. 1615-1618. BMJ Publishing Group 10.1136/bjophthalmol-2018-313048

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AIM To describe the optical coherence tomography (OCT) characteristics and to identify and analyse the incidence of choroidal neovascular (CNV) network seen on optical coherence tomography angiography (OCTA) in eyes with cystoid macular degeneration (CMD) associated with central serous chorioretinopathy (CSCR). METHODS This was a retrospective, observational study of 29 eyes of 25 patients who were previously diagnosed as CSCR with CMD. Baseline patient characteristics, best-corrected visual acuity (BCVA), evidence of CNV network and its pattern on OCTA, distribution of CMD changes and OCT parameters, such as height of the neurosensory retinal detachment (NSD), presence of double layer sign, central macular thickness, were analysed. The eyes were classified into two groups depending on the presence or absence of CNV network on OCTA. BCVA, OCT parameters and CMD distribution were compared in the two groups at baseline using independent t-test. RESULT A total of 13 (44.8 %) eyes had a CNV network, while only 9 out of the 13 eyes had pattern-I CNV. Among the eyes with CNV network (13 eyes), mean height of NSD was of 65.2±22.7 µ, whereas, among the eyes without CNV (16 eyes), it was 134.6±77.4 µ. The difference was statistically significant (p=0.013). There was no statistically significant difference between eye having a CNV and eyes without CNV in terms of other parameters. CONCLUSION A CNV network is seen in a large subset of patients with CMD in CSCR. A shallower subretinal fluid may point towards the presence of an underlying CNV network.

Item Type:

Journal Article (Original Article)


04 Faculty of Medicine > Department of Head Organs and Neurology (DKNS) > Clinic of Ophthalmology

UniBE Contributor:

Munk, Marion and Berger, Lieselotte Erika


600 Technology > 610 Medicine & health




BMJ Publishing Group




Marion Munk

Date Deposited:

29 Jan 2019 15:16

Last Modified:

26 Oct 2019 01:30

Publisher DOI:


PubMed ID:


Uncontrolled Keywords:

CSCR OCT angiography central serous chorioretinopathy choroidal neovascularisation cystoid macular degeneration





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