Rhombencephalitis Caused by Listeria monocytogenes in Humans and Ruminants: A Zoonosis on the Rise?

Oevermann, Anna; Zurbriggen, Andreas; Vandevelde, Marc (2010). Rhombencephalitis Caused by Listeria monocytogenes in Humans and Ruminants: A Zoonosis on the Rise? Interdisciplinary perspectives on infectious diseases, 2010, pp. 1-22. Cairo (Egypt): Hindawi Pub. Corp. 10.1155/2010/632513

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Listeriosis is an emerging zoonotic infection of humans and ruminants worldwide caused by Listeria monocytogenes (LM). In both host species, CNS disease accounts for the high mortality associated with listeriosis and includes rhombencephalitis, whose neuropathology is strikingly similar in humans and ruminants. This review discusses the current knowledge about listeric encephalitis, and involved host and bacterial factors. There is an urgent need to study the molecular mechanisms of neuropathogenesis, which are poorly understood. Such studies will provide a basis for the development of new therapeutic strategies that aim to prevent LM from invading the brain and spread within the CNS.

Item Type:

Journal Article (Original Article)

Division/Institute:

05 Veterinary Medicine > Department of Clinical Research and Veterinary Public Health (DCR-VPH) > Experimental Clinical Research
05 Veterinary Medicine > Department of Clinical Veterinary Medicine (DKV) > DKV - Clinical Neurology

UniBE Contributor:

Oevermann, Anna; Zurbriggen, Andreas and Vandevelde, Marc

ISSN:

1687-708X

Publisher:

Hindawi Pub. Corp.

Language:

English

Submitter:

Factscience Import

Date Deposited:

04 Oct 2013 14:32

Last Modified:

08 Jun 2016 10:29

Publisher DOI:

10.1155/2010/632513

BORIS DOI:

10.7892/boris.12366

URI:

https://boris.unibe.ch/id/eprint/12366 (FactScience: 218698)

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