English Translation and Validation of the Zurich Chronic Middle Ear Inventory (ZCMEI-21-E) Assessing Quality of Life in Chronic Otitis Media: A Prospective International Multicenter Study.

Chatzimichalis, Michail; Epprecht, Lorenz; Weder, Stefan; Shaul, Chanan; Engle Folchert, Kristi J; Machala, Maria C; Goosmann, Madeline M; Naville, Marc; Zhu, Angela; Röösli, Christof; Lee, Daniel J; Cass, Stephen P; Briggs, Robert; Huber, Alexander M; Bächinger, David (2019). English Translation and Validation of the Zurich Chronic Middle Ear Inventory (ZCMEI-21-E) Assessing Quality of Life in Chronic Otitis Media: A Prospective International Multicenter Study. Clinical otolaryngology, 44(3), pp. 254-262. Wiley 10.1111/coa.13275

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OBJECTIVES To translate and validate the Zurich Chronic Middle Ear Inventory (ZCMEI-21) for the English language in order to provide an English instrument to assess health-related quality of life in chronic otitis media (COM). DESIGN Pilot translation study including cognitive debriefings, prospective multicenter cross-sectional psychometric validation study. SETTING Four tertiary referral centers in three different English-speaking countries (United Kingdom, United States of America and Australia). PARTICIPANTS Adult patients suffering from COM. MAIN OUTCOME MEASURES The English translation of the ZCMEI-21 (ZCMEI-21-E) and the five-level version of the EQ-5D questionnaire. The EQ-5D, which constitutes a generic measure of health-related quality of life, consists of a descriptive system score and a visual analogue scale. Statistical outcomes included single item descriptive statistics, internal consistency (Cronbach's α) as an indicator of reliability, as well as construct validity. RESULTS A total of 124 patients suffering from COM were included. The mean age was 50.1 years (SD 16.9 years) and 72 (58.1%) were males. The Cronbach's α of the ZCMEI-21-E was 0.91, suggesting an excellent internal consistency. The Spearman's correlation coefficient of the ZCMEI-21-E total score was 0.55 (p < 0.0001) for convergent construct validity with EQ-5D descriptive system score and 0.57 (p < 0.0001) with the EQ-5D visual analogue scale. CONCLUSIONS The ZCMEI-21-E is a new validated questionnaire that provides clinicians with a short, comprehensive and reliable instrument to quantify health-related quality of life in patients suffering from COM. The ZCMEI-21-E may be of use in clinical routine as well as in outcome research and monitoring. This article is protected by copyright. All rights reserved.

Item Type:

Journal Article (Original Article)

Division/Institute:

04 Faculty of Medicine > Department of Head Organs and Neurology (DKNS) > Clinic of Ear, Nose and Throat Disorders (ENT)

UniBE Contributor:

Weder, Stefan

Subjects:

600 Technology > 610 Medicine & health

ISSN:

1749-4478

Publisher:

Wiley

Language:

English

Submitter:

Stefan Weder

Date Deposited:

23 Jan 2019 15:08

Last Modified:

25 Oct 2019 08:55

Publisher DOI:

10.1111/coa.13275

PubMed ID:

30588758

Uncontrolled Keywords:

English HRQoL Otology ZCMEI-21 cholesteatoma chronic otitis media electronic patient-reported outcome measure questionnaire translation

BORIS DOI:

10.7892/boris.123703

URI:

https://boris.unibe.ch/id/eprint/123703

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