Cournand's and Richards' Post-Nobel Challenge: "Do Anything on the Structure of the Lung That Is of Interest for Physiology".

Weibel, Ewald Rudolf (2018). Cournand's and Richards' Post-Nobel Challenge: "Do Anything on the Structure of the Lung That Is of Interest for Physiology". Annals of the American Thoracic Society, 15(Supplement1), S4-S8. American Thoracic Society 10.1513/AnnalsATS.201705-398KV

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In their Nobel Lectures of 1956, the two cardiopulmonary physiologists André Cournand and Dickinson Richards described the future projects that they considered important for rounding up their impressive scientific achievements. One of them called for work that brought together structure and function of the lung in a systematic way. They challenged a young anatomist to undertake this in their cardiopulmonary laboratory at Bellevue Hospital. The first steps established the need for quantitative information on the structures that form the pulmonary gas exchanger as well as the airway tree. This resulted in a new approach to lung anatomy: morphometry would provide the quantitative information for modeling structure-function relations in the lung, and eventually in the entire respiratory system, thus allowing a rational analysis of how structures affect or limit functions.

Item Type:

Journal Article (Further Contribution)

Division/Institute:

04 Faculty of Medicine > Pre-clinic Human Medicine > Institute of Anatomy

UniBE Contributor:

Weibel, Ewald Rudolf

Subjects:

600 Technology > 610 Medicine & health

ISSN:

2325-6621

Publisher:

American Thoracic Society

Language:

English

Submitter:

Benoît Zuber

Date Deposited:

22 Feb 2019 13:37

Last Modified:

23 Oct 2019 11:18

Publisher DOI:

10.1513/AnnalsATS.201705-398KV

PubMed ID:

29461884

Uncontrolled Keywords:

cell biology diffusing capacity lung morphometry stereology structure and function

BORIS DOI:

10.7892/boris.124044

URI:

https://boris.unibe.ch/id/eprint/124044

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